A 77-year-old woman complaining of anorexia and nausea was referred to the hospital with a diagnosis of advanced gastric cancer. The patient also had congestive heart failure with atrial fibrillation and severe hypoproteinemia. Proteinuria, hypoproteinemia and other laboratory data suggested that she had nephrotic syndrome. Total protein level was 4.6 g/dl and albumin level was 1.6 g/dl. In ord...

Splenic littoral cell angioma (LCA) is a comparatively rare vascular neoplasm of the spleen. LCA always presents with thrombocytopenia, fever, weight loss, and abdominal pain, and may also involve splenic rupture. To our knowledge, however, splenic LCA is rarely accompanied by severe hypoproteinemia. This report describes a 36-year-old woman with multiple splenic LCA, accompanied by severe hypo...

The serum protein concentration has frequently been observed to be reduced in certain types of Bright's disease and in various types of malnutrition. Formerly the fundamental cause for this was attributed to either a loss of protein in the urine or a lack of protein in the diet. In 1933, in introducng studies on the effect of restriction of protein intake on the serum protein concentration of t...

primary intestinal lymphangiectasia (pil) is a rare disease of intestinal lymphatics presenting with hypoproteinemia, bilateral lower limb edema, ascites and protein-losing enteropathy. we report a case of pil in a 22 year old patient from tabriz, iran who presented with anasarca edema, recurrent diarrhea, hypoproteinemia and confirmatory features of pil on endoscopy and histopathology. therefo...

Protein-losing gastroenteropathies are characterized by an excessive loss of serum proteins into the gastrointestinal tract, resulting in hypoproteinemia (detected as hypoalbuminemia), edema, and, in some cases, pleural and pericardial effusions. Protein-losing gastroenteropathies can be caused by a diverse group of disorders and should be suspected in a patient with hypoproteinemia in whom oth...

Silvery hair is a characteristic finding of 3 rare autosomal recessive disorders: Chédiak-Higashi syndrome (CHS), Elejalde syndrome (ES), and Griscelli syndrome (GS). We report the case of a 2-month-old male infant with transient silvery hair and generalized hypopigmentation of the skin and eyes who did not have one of these classic causative disorders. The patient was delivered at 35 weeks' ge...

background: the aim of this study was to evaluate maternal and perinatal outcomes in preeclampsia (pe), according to the value of albumin.materials and methods: preeclamptic women were retrospectively divided into mild hypoproteinemia (mhp, n = 220) and severe hypoproteinemia (shp, n = 79) pe according to the value of albumin. the maternal and perinatal outcomes were evaluated in both groups. r...

Crizotinib, which is effective in patients with anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer, is sometimes associated with the generation of complex renal cysts. A 56-year-old man with ALK positive adenocarcinoma received crizotinib. Ten months after the introduction of crizotinib, a cystic lesion developed from his right kidney to the iliopsoas muscle, accompanied by fe...