BACKGROUND Hypoglycemic coma is a continuous threat for diabetic patients treated with insulin and/or oral hypoglycemic agents; it may be associated with substantial morbidity and mortality. METHODS We retrospectively reviewed our clinical experience with drug-induced hypoglycemic coma during a 7-year period. RESULTS The study consisted of 102 patients and included 61 females and 41 males. ...

calendula officinalis (family compositae) flowers are recognized as safe substance for food use by food and drug administration. present study was aimed to determine the modulatory effect of floral extracts of c. officinalis administrations on mean blood glucose (mbg), per cent glycosylated hemoglobin (hba1c), lipid profile [(total cholesterol (tc), triglycerides (tg), low and high density lipo...

the aim of this study was to assess the antiglycation and antioxidant properties of aqueous extract of anethum graveolens (dill). in the in vivo and in vitro experiments, antioxidant properties, blood glucose, and ages formation were determined. dill extract was given orally to healthy and diabetic rats. our results illustrated that different concentrations of dill extract (0.125, 0.25, 0.5, an...

background: glybenclamide and metformin are two of the most common oral hypoglycemic drugs which are often used in treatment of type ii diabetes mellitus. toxicity due to these drugs may occur intentionally, accidentally, or even at the normal dosage because of the progression of such internal diseases as renal dysfunction. methods: in this case series study, 59 patients poisoned with oral hypo...

BACKGROUND Under current European Union legislation, two severe hypoglycemic events within 12 months is grounds for driving license withdrawal. The aim of the study reported here was to determine whether fear of such a withdrawal could lead to patients concealing severe hypoglycemia from physicians, which could negatively impact further treatment decisions. METHODS A total of 663 patients wit...

OBJECTIVE Antecedent hypoglycemia reduces hypoglycemic counterregulation and symptoms, thereby provoking the hypoglycemia unawareness syndrome. The effects of antecedent hypoglycemia on hypoglycemia-induced cognitive dysfunction are less well established. RESEARCH DESIGN AND METHODS To determine whether antecedent hypoglycemia also reduces hypoglycemic cognitive dysfunction, we performed step...

Aloe buettneri was evaluated to confirm its hypoglycemic activity. The presence of quinone which seem to leave the hypoglycemic activity. Lyophilisate of A. buettneri leaf (LA) causes hypoglycemia only 2 h after its administration and is linked to the presence of quinone. Glycemia reduction with LA was significantly higher than that of Glibenclamide, the control. Glibenclamide and LA negatively...

Changes in serum free amino acids as a response to ketogenic provocative test were studied in children with a history of ketosis but without hypoglycemia. 1. Of the 17 children who underwent the provocative test, only three showed clinical manifestations. They were among five children who responded to the test and developed hypoglycemia. 2. Hypoglycemic and non-hypoglycemic children differed gr...