UNLABELLED Infective endocarditis in hypertrophic obstructive cardiomyopathy is rare. Management of this disease is challenging due to the unique features of dynamic pressure gradient over the left ventricular outflow tract and its unpredictable interaction with the management of sepsis. The added complexity of infective endocarditis further complicates an already difficult situation. A 72-year...

An 18-year-old man with known hypertrophic obstructive cardiomyopathy since age 9 was referred for evaluation. His mother had died suddenly at age 24, and her autopsy demonstrated hypertrophic obstructive cardiomyopathy. The patient was asymptomatic. His only medication was propranolol. Two-dimensional echocardiographic images demonstrated normal left ventricular size with hyperdynamic function...

Hypertrophic obstructive cardiomyopathy is the most common genetic cardiac disease and is generally characterised by asymmetric septal hypertrophy and intraventricular obstruction. Patients with severe obstruction and significant symptoms that persist despite optimal medical treatment are candidates for an invasive septal reduction therapy. Twenty years after its introduction, percutaneous tran...

Introduction Mutations in PKD1 and PKD2 cause autosomal dominant polycystic kidney disease (ADPKD). Experimental evidence suggests an important role of the polycystins in cardiac development and myocardial function. To determine whether ADPKD may predispose to the development of cardiomyopathy, we have evaluated the coexistence of diagnoses of ADPKD and primary cardiomyopathy in our patients. ...

structive hypertrophic cardiomyopathy. J Clin Invest 66: 1369, 1980 30. Stefadouros MA, Canedo MI, Karayannis E, Abdulla A, Frank MJ: Internally recorded systolic time intervals in hypertrophic subaortic stenosis. Am J Cardiol 40: 700, 1977 31. Nesje OA, Enge I: External carotid pulse recordings in hypertrophic obstructive cardiomyopathy. Acta Med Scand 202: 197, 1977 32. Henry WL, Clark CE, Gr...

structive hypertrophic cardiomyopathy. J Clin Invest 66: 1369, 1980 30. Stefadouros MA, Canedo MI, Karayannis E, Abdulla A, Frank MJ: Internally recorded systolic time intervals in hypertrophic subaortic stenosis. Am J Cardiol 40: 700, 1977 31. Nesje OA, Enge I: External carotid pulse recordings in hypertrophic obstructive cardiomyopathy. Acta Med Scand 202: 197, 1977 32. Henry WL, Clark CE, Gr...

OBJECTIVE The appearance of atrial fibrillation is associated with significant clinical deterioration in patients with obstructive hypertrophic cardiomyopathy; therefore, maintenance of sinus rhythm is desirable. Guidelines and most articles have reported the results of catheter ablation and pharmacologic atrial fibrillation treatment; nevertheless, data regarding concomitant procedures during ...

CHEST, 77: 3, MARCH, 1980 obstructive hypertrophic cardiomyopathy and discrete subaortic stenosis, since this abnormality is seen commonly in both conditions. As pointed out by Dr. Glaser, a recent article by Krajcer et al describes a consistent difference in the timing of midsystolic closure of the aortic valve: in each of 22 patients with obstructive hypertrophic cardiomyopathy, midsystolic a...