The roles of vasodilator metabolites and/or reduced local intra-arteriolar pressure in producing the reactive hyperemia which follows the suclden release of arterial occlusion were studied. It was found that slight increases of metabolic activity during the period of occlusion increased the reactive hyperemia considerably. Maintenance of intra-arteriolar pi'essure during arterial occlusion depr...

PURPOSE Bimatoprost is a potent hypotensive drug used in the treatment of glaucoma or ocular hypertension with lower target intraocular pressure (IOP) than latanoprost. Its most disturbing side effect is conjunctival hyperemia. The authors compared the extent of conjunctival hyperemia in patients receiving bimatoprost as initial therapy with that in patients whose treatment with latanoprost was...

Elevated blood flow (reactive hyperemia) is seen in many organs after a period of blood flow stoppage. This hyperemia is often considered to be due in part to a shift to anaerobic metabolism during tissue hypoxia. The aim of our study was to test this hypothesis in skeletal muscle. For this purpose we measured NADH fluorescence at localized tissue areas in cat sartorius muscle during and after ...

BACKGROUND Peripheral vascular endothelial dysfunction is an independent predictor of cardiovascular events, and can be assessed noninvasively by measuring reactive hyperemia, either by vascular ultrasound measurement of flow-mediated vasodilatation or, less commonly, by measurement of blood flow using plethysmography. In the present study reactive hyperemia was measured using plethysmography i...

Objective: To evaluate the usefulness and prognostic value of reactive hyperemia - peripheral arterial tonometry in patients with sepsis. Moreover, we investigated the association of reactive hyperemia - peripheral arterial tonometry results with serum levels of certain inflammatory molecules. Methods: Prospective study, conducted in an 18-bed mixed intensive care unit for adults. The exclusi...

hyperemia directly after release of the blood pressure cuff. As stated in our article, we did not measure reactive hyperemia but performed our measurements in all groups after 20 min of reperfusion. It is, therefore, unlikely that reactive hyperemia caused the observed differences between groups. We agree that further studies are needed to clarify more the mechanisms of helium preconditioning i...

During reactive hyperemia following a brief coronary artery occlusion, excess arterial inflow exceeds the blood flow debt incurred during occlusion by 300-600T. The present study was performed to determine whether this marked reactive hyperemia is essential for restoration of coronary vascular tone. Coronary blood flow was measured in unanesthetized dogs with electromagnetic flowmeters and hydr...