background: hypercholesterolemia is one of the risk factors of cardiovascular diseases. it affects general health and increases cardiovascular mortality rate. diet with high cholesterol increases ldl that, inturn, decrease ldl receptors activity in liver. oxidation of vessel wall lipoproteins increases development of atherosclerosis. several evidences suggest that antioxidants consumption decre...

objectives: liver is one of the most sensitive tissues to oxidant damage. hence, the present study was conducted to compare the effects of melissa officinalis (mo) extract and atorvastatin on the activity of liver enzymes in rats. materials and methods: in this experimental study, 60 male wistar rats were selected and allocated to six groups (n=10). the control group received a normal diet, sha...

familial defective apolipoprotein (apo) b 100 (fdb) causes early-onset coronary heart diseases (chd). it is produced by r3500q mutation of the apob gene resulting in decreased binding of ldl to ldl receptor. we screened the apo b gene for r3500q mutation in 130 hypercholesterolemic patients, among whom 30 patients met criteria of familial hypercholesterolemia (fh). the prevalence of r3500q alle...

conclusions decreases of tc, ldl and tg may be related to tomato antioxidant effect. this course in human required more investigations. results results showed that in chol group, all lipids increased significantly (p < 0.05) except hdl compared to the control group. tomato and tomato paste supplementation decreased tc, ldl and tg concentration significantly (p < 0.05) compared to chol group. to...

Hypercholesterolemia is one of the potential risks cardiovascular heart disease (CHD). An early diagnosis and treatment attenuate risk CHD. Besides statin prescription for hypercholesterolemia, functional food has an added value to ameliorate risk. This study was conducted analyse significant effect grey oyster mushroom (Pleurotus pulmonarius) on hypercholesterolemia. Thirty-six Wistar-Kyoto ra...

INTRODUCTION Pediatric hypercholesterolemia has increased over the past decades. Knowing the environmental and genetic factors that have an impact on it would allow establishing more adequate screening guidelines. OBJETIVES To determine if there is an association between genetic and environmental factors and hypercholesterolemia in children. To assess the predictive qualities of outcome measu...

The aim of this study was to determine the anticholesterol activity stem extract Uncaria cordata (Lour.) Merr. on total cholesterol levels in male mice (Mus musculus). Before carrying out test, phytochemical tests were carried content secondary metabolites stems. Furthermore, test vivo using mice, induced by high-fat diet (PTL) form beef brain, quail egg yolk and propylthiouracil increase until...