Hypercalcaemia is frequently found during routine blood screening and often remains asymptomatic for a prolonged period until serious renal or bone complications reveal its presence.'2 Symptoms of hypercalcaemia also may be marked by nonspecific gastrointestinal or neuropsychiatric complaints. It is therefore not unexpected that routine serum calcium analysis by auto-analyser techniques is freq...

Recurrent hypercalcaemia associated with hypersensitivity to ultra violet light occurring in a patient who had had clinical sarcoidosis 14 years previously. Hypercalcaemia in sarcoidosis is a well known association, but it is less often realized that this hypercalcaemia may undergo seasonal variation (Taylor, Lynch and Wyser, 1963). The following case report describes recurring seasonal symptom...

Acute kidney injury is rarely the presenting feature of sarcoidosis. We report case a patient whose diagnosis was brought to light by investigation impaired function. Concurrent hypercalcaemia noted and prompted further investigation, which led This rare phenomenon an important consideration in with acute hypercalcaemia, without apparent explanation. Rapid improvement both function occurred res...

A 32 year old man presented on two separate occasions with severe hypercalcaemia. Both episodes followed the fracture of a single pagetic bone but were not associated with immobilization. To our knowledge this patient, the youngest described with hypercalcaemia secondary to Paget's disease of bone is also the only reported case of recurrent hypercalcaemia in this condition.

We report the case of a 64-year-old man who presented with severe hypercalcaemia secondary to primary hyperparathyroidism. Soon after admission he developed ventricular fibrillation with no other cause than this severe hypercalcaemia. Although the occurrence of cardiac arrhythmias in hypercalcaemia is widely known, ventricular fibrillation has never been described before.

Hypercalcaemia as the only manifestation of B-cell lymphoma is seen very rarely. Its pathophysiology is heterogenous and not well understood. We report a 73-year-old man who presented with severe hypercalcaemia before any signs of malignancy became evident. He was diagnosed with a B-cell lymphoma on bone marrow trephine biopsy. The hypercalcaemia was associated with high plasma concentrations o...

In two patients with extensive pulmonary tuberculosis who developed hypercalcaemia and hypokalaemia the hypercalcaemia appeared related to the use of small doses of vitamin D, which suggested patients with tuberculosis were hypersensitive to vitamin D. They were thus similar to patients with sarcoidosis, and it is interesting that the Kveim test result was positive in both cases. The hypercalca...

BACKGROUND Williams-Beuren syndrome (WBS) is a rare genetic disorder caused by the deletion of 26-28 genes on chromosome 7. Fifteen percent of WBS patients present with hypercalcaemia during infancy, which is generally mild and resolves spontaneously before the age of 4 years. The mechanisms underlying the transient hypercalcaemia in WBS are poorly understood. CASE We report a case of severe ...

more patients undergoing routine blood tests for other purposes. However, not all cases require treatment. Primary hyperparathyroidism and malignancy together account for 90% of all hypercalcaemic patients.1 Aetiology varies according to the clinical presentation; more indolent cases suggest hyper­ parathyroidism, and more rapidly developing cases suggest malignancy. About 20­30% of all patient...

A 7-year-old female beagle was evaluated for symptomatic hypercalcaemia and primary hypothyroidism. Clinical findings were typical for hypothyroidism. Plasma parathyroid hormone was low and obvious causes for the hypercalcaemia were ruled out by means of abdominal ultrasonography, ultrasonography of the parathyroid glands, survey thoracic radiographs, and fine needle aspirate cytology of the sp...