Ionizing radiation (IR) is commonly used in cancer therapy and is a main source of DNA double-strand breaks (DSBs), one of the most toxic forms of DNA damage. We have used Caenorhabditis elegans as an invertebrate model to identify novel factors required for repair of DNA damage inflicted by IR. We have performed an unbiased genetic screen, finding that smg-1 mutations confer strong hyper-sensi...

In this paper, a novel fractional-order hyper-chaotic system is proposed. By drawing the phase trajectory and Lyapunov exponent spectrum, its dynamic characteristics are analyzed. The simulation results show that the fractional-order hyper-chaotic system has hyper-chaotic characteristic. Then, image encryption implementation based on the fractional-order hyper-chaotic system is investigated. An...

Applying state of the art deeplearning models to novel real world datasets gives a practical evaluation of the generalizability of these models. Of importance in this process is how sensitive the hyper parameters of such models are to novel datasets as this would affect the reproducibility of a model. We present work to characterize the hyper parameter space of an LSTM for language modeling on ...

in this note first we define the notions of fuzzy positive implicativehyper bck-ideals of types 1,2,3 and 4. then we prove some theorems whichcharacterize the above notions according to the level subsets. also we obtainthe relationships among these notions, fuzzy (strong, weak, reflexive) hyperbck-ideals and fuzzy positive implicative hyper bck-ideals of types 5,6,7and 8. then, we define the no...

in this paper, we aresupposed to introduce the definitions of n-fold commutative, andimplicative hyper k-ideals. these definitions are thegeneralizations of the definitions of commutative, andimplicative hyper k-ideals, respectively, which have been definedin [12]. then we obtain some related results. in particular wedetermine the relationships between n-fold implicative hyperk-ideal and n-fold...

High mobility group AT-hook 1 (HMGA1) protein is an oncogenic architectural transcription factor that plays an essential role in early development, but it is also implicated in many human cancers. Elevated levels of HMGA1 in cancer cells cause misregulation of gene expression and are associated with increased cancer cell proliferation and increased chemotherapy resistance. We have devised a str...