BACKGROUND Various drugs have been tried to hasten cervical dilatation so that problems and hazards of prolonged labour both for the mother and fetus are minimised without increasing maternal or perinatal mortality and morbidity. AIMS AND OBJECTIVES To compare the effect of camylofin dihydrochloride with combination of valethemate bromide (epidosin) & hyoscine N butyl bromide (buscopan) on ce...

Cyclotropium bromide, a new antimuscarinic agent, inhibits gastrointestinal motility in animals at lower doses than those required to inhibit gastric acid secretion and salivation. In man, cyclotropium bromide suppresses fasting and meal stimulated colonic motility. This study investigated the effects of single oral doses of 60 mg cyclotropium bromide, 60 mg hyoscine N-butylbromide and placebo ...

In our case, dipyridamole-induced ischemia is an unlikely cause. This may suggest the depressive action of dipyridamole through adenosine on the conducting system. We feel that dipyridamole is the probable cause of asystole in this individual, based on a score of 5 on Naranjo’s algorithm, and betablocking agents may have contributed to this.[6] In patients with underlying conduction abnormaliti...

BACKGROUND Hyoscine N-butyl bromide (HBB) acts by inhibiting cholinergic transmission in the abdomino-pelvic parasympathetic ganglia, thus relieving spasm in the smooth muscles of gastrointestinal, biliary, urinary tract and female genital organs, especially the cervico-uterine plexus and aiding cervical dilatation. AIM The study was undertaken to observe the effects of 40 mg intravenous HBB ...