BACKGROUND Prolonged labor is one of the most important risk factors for perinatal compromise and, if caused by obstructed labor, it carries the risk of uterine rupture, postpartum hemorrhage (PPH), puerperal sepsis, and maternal death. OBJECTIVE To determine whether or not hyoscine butylbromide shortens the stages of labor, without an increase in maternal or neonatal complications. METHOD ...

Bowel sounds were heard in 42 cases from group A compared with 13 from group B (X2 test, P <0 001). When it became likely that an effect was present (after 50 cases) the scope of the investigation was widened to include observations of the bowel sounds 30 and 60 minutes later by trained recovery room staff who did not know which drugs had been injected. Of 31 patients from group A, 24 had audib...

OBJECTIVE To investigate the evidence for the use of hyoscine N-butylbromide (HBB) in the treatment of acute renal colic. METHODS A literature search was performed using the keywords 'hyoscine N-butylbromide', 'ureteral colic', 'spasmolytic', 'anticholinergic' and 'analgesia'. The articles were given the appropriate level of evidence according to the Oxford Centre for Evidence-Based Medicine ...

Purpose: Peristalsis of the small bowel leads to considerable movement artifacts in MR-examinations, which hamper diagnostic quality [1, 2]. Therefore a spasmolytic premedication agent is commonly administered intravenously to inhibit bowel motion, shortly before performing the abdominal imaging studies. Two main paralyzing agents, hyoscine N-butylbromide (HBB; Buscopan Boehringer Ingelheim, Ge...

17. King JC. Anisotropine methylbromide for relief of gastrointestinal spasm: doubleblind crossover comparison study with belladonna alkaloids and phenobarbital. Curr Ther Res Clin Exp 1966;8(11):535-541. View Abstract 18. Lichstein J, Mayer JD. Drug therapy in the unstable bowel (irritable colon). A 15-month double-blind clinical study in 75 cases of response to a prolonged-acting belladonna a...