Abstract Background The plant Hymenocardia acida (Euphorbiaceae) is utilized as herbal preparation against diarrhoea, dysentery and other diseases. We aimed to determine the antidiarrhoeal potentials of (MEHA) stem bark in vivo vitro. Preliminary phytochemical contents, well acute toxicity effect extract, were investigated based on standard experimental methods. properties MEHA at 150, 300 600 ...

The toxicity and mutagenic potential of most African plants implicated in the management of cancer have not been investigated. The ethanolic extracts of selected Nigerian plants were subsequently studied using the brine shrimp lethality tests, inhibition of telomerase activity and induction of chromosomal aberrations in vivo in rat lymphocytes. Morinda lucida root bark, Nymphaea lotus whole pla...

The genus Hymenocardia has been placed either in Euphorbiaceae subfamily Phyllanthoideae or in its own family and then associated with the Urticales, particularly the Ulmaceae. However, the pollen exine wall of Hymenocardia lacks the microchanneled tectum, granular interstitium, and thin foot-layer of the Urticales. Hymenocardia instead has many palynological features found in the Phyllanthoide...

The in vitro antitrypanosomal activity of methylene chloride, methanol and aqueous extracts of the leaves and twigs of five plant species traditionally used in Benin for the treatment of sleeping sickness were evaluated on Trypanosoma brucei brucei and their selectivity was analysed on Leishmania mexicana mexicana and J774 macrophage-like murine cells. The results showed that the four most acti...