A problem of long standing in the study of dentin and enamel is the exact nature and structure of the inorganic material in these tissues. A review of these studies from the time of Berzelius in 1845 up to 1949 has been published by Armstrong (1). In general the mineral component of teeth as well as bones consists chiefly of a basic calcium phosphate which is most probably hydroxyapatite (2, 3)...

A problem of long standing in the study of dentin and enamel is the exact nature and structure of the inorganic material in these tissues. A review of these studies from the time of Berzelius in 1845 up to 1949 has been published by Armstrong (1). In general the mineral component of teeth as well as bones consists chiefly of a basic calcium phosphate which is most probably hydroxyapatite (2, 3)...

Due to its similarity with biological apatite found in vertebrate hard tissues, calcium hydroxyapatite is one of the most investigated materials bone tissue engineering. As not stoichiometric, ion substituted hydroxyapatites attract much atention since they more closely mimic composition natural bone. Although there are many investigations influence foreign ions on structure and physico-chemica...

BACKGROUND Ceramic hydroxyapatites and non-ceramic hydroxyapatites have been used extensively as alloplastic materials for bone reconstruction. However, different forms of hydroxyapatite induce different types of tissue response. METHODS Human gingival fibroblasts (FMM1 cells) were used to analyze ceramic and non-ceramic hydroxyapatite biocompatibility. The cells were grown on surfaces covere...