Amyloid fibrils are large aggregates of misfolded proteins, which are often associated with various neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and vascular dementia. The amount of hydrogen sulfide (H2S) is known to be significantly reduced in the brain tissue of people diagnosed with Alzheimer's disease relative to that of healthy individuals. These findings prom...

Substituted bis(iminophosphoranyl)methanes are CH acidic compounds that can form 15 complexes with formally dianionic central carbon centres. The reaction of H2C(Ph2P=NDip)2 (≡ 16 H2L), Dip = 2,6-diisopropylphenyl, with one equivalent of di-n-butylmagnesium afforded the 17 methanide complex [HLMgnBu] 1. Treatment of complex 1 with phenylsilane in aromatic solvents 18 at elevated temperatures af...

The formation constants of the species formed in the systems fr + glycine + dioxovanadium(V) + and H+ + glycine have been determined in aqueous solutions of methanol at 25 °C and constant ionicstrength, using spectrophotometric and potentiometric techniques. It was shown thatdioxovanadium(V) forms two mononuclear 1 : land 1:2 complexes with glycine. The formationconstants in various media were ...

In the present work, an extensive theoretical calculation study on Histidine-Histidine dipeptide in gas phase is done by using DFT method with Gaussian 98 program. Through investigations on the molecular geometries of this molecule it is found that there is six rings in the molecules not two rings. The presence of four intramolecular hydrogen bonds is responsible for the formation of additional...