The purpose of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. The recent developments of FDDS including the physiological and formulation variables affecting gastric retention, approaches to design single-unit and multiple-unit floating systems, and their ...

The objective of the present study was to formulate hydrodynamically balanced systems (HBSs) of theophylline as single unit capsules. They were formulated by physical blending of theophylline with hydroxypropyl methyl cellulose, polyethylene oxide, polyvinyl pyrrolidone, ethyl cellulose, liquid paraffin, and lactose in different ratios. These theophylline HBS capsules were evaluated for weight ...

Conventional oral dosage forms suffer with many disadvantages. To avoid such limitations controlled release dosage forms are preferred. When these controlled release dosage forms administered by oral route retained in the stomach and release the drug in a controlled fashion continuously in gastrointestinal tract [1]. Controlled release systems also suffer with some limitations such as short gas...

background; the performance of the hse units has various dimensions leading to different performances. thus, any industry should be capable of evaluating these systems. the aim of this study was to design a standard questionnaire in the field of performance evaluation of hse management system employing balanced score card model. methods; in this study we, first determined the criteria to be eva...

Artificial neural networks (ANNs) were used as modeling tools for prediction of various drugs release patterns from hydrodynamically balanced systems (HBS) composed with Metholose 90SH (hydroxypropylmethylcellulose--HPMC). The objective was to provide predictive and data-mining models of analyzed problem. It was found that ANNs are capable to accurately predict release patterns of different dru...