OBJECTIVE To investigate a possible direct, growth hormone-releasing, hormone-independent action of a growth hormone secretagogue, GHRP-2, in pituitary somatotroph cells in the presence of inactive growth hormone-releasing hormone receptors. MATERIALS AND METHODS The responses of serum growth hormone to acutely injected growth hormone-releasing P-2 in lit/lit mice, which represent a model of ...

A field trail was conducted at Cental Research Farm, SHUATS, Naini, Prayagraj, U.P. during kharif season of 2021 in Randomised Block Design with eight treatments were evaluated against, Spodoptera frugiperda i.e., Spinetoram 11.7%SC @0.9ml/lit, Chlorantraniliprole 18.5%SC @0.4ml/lit, Flubendiamide 39.35%SC @0.24ml/lit, Emamectin benzoate 5%SG @0.4g/lit, Neem oil 2% @5mi/lit, NPV @0.5ml/lit, Nov...

Glial cells surround neuronal endings to create enclosed compartments required for neuronal function. This architecture is seen at excitatory synapses and at sensory neuron receptive endings. Despite the prevalence and importance of these compartments, how they form is not known. We used the main sensory organ of C. elegans, the amphid, to investigate this issue. daf-6/Patched-related is a glia...

The effect of growth hormone (GH) on binding of epidermal growth factor (EGF) to liver membrane preparations was investigated in hypophysectomized mice and partially GH-deficient, genetic mutant "little" (lit/lit) mice. The EGF binding of normal male mice and testosterone-treated females was higher than in normal females. Due to diminished receptor concentration, hepatic EGF binding was decreas...

BACKGROUND Mice sensitized to ovalbumin develop allergic airway disease (AAD) with short-term aerosol challenge; however, airway inflammation resolves with long-term aerosol challenge, referred to as local inhalational tolerance (LIT). METHODS We sought to determine if resolution of airway inflammation correlated with increases in lymphocyte subsets in local lung compartments, including putat...

Obesity as a common health risk is increasing all over the world. The aim of this study was evaluation of standing and sitting positions on spirometric values in obese asthmatic patients, in comparison with normal obese subjects. The study included 49 obese asthmatic patients with mean age of 42.63 years and body mass index of 36.06 kg/m2, and 51 control obese normal subjects with mean age of 3...