A projected hybrid orbital (PHO) method was described to model the covalent boundary in a hybrid quantum mechanical and molecular mechanical (QM/MM) system. The PHO approach can be used in ab initio wave function theory and in density functional theory with any basis set without introducing system-dependent parameters. In this method, a secondary basis set on the boundary atom is introduced to ...

Received: December 28, 2017 Revised: February 23, 2018 Accepted: February 26, 2018 Abstract: Background: For centuries, steel rebar has been the primary reinforcement in concrete despite its major drawbacks, such as its heavy weight, high electrical conductivity, and corrosiveness. Thus, in response to the need for better alternatives, innovative Hybrid Composite (HC) reinforcements have been d...

In practice the systems are not only pure discrete event or pure continuous, but they are combined from discrete and continuous parts together. These systems are called hybrid systems. Hybrid Petri nets (HPNs) allow modeling and analysis of hybrid systems. Since classical HPNs cannot properly model the systems with the delays on continuous product flow, extended Hybrid Petri nets and generalize...

Lots of diagnosis approaches proposed in the literature are based in the assumption of single faults. This assumption may result to erroneous diagnosis statement in case where multiple faults occurs. Thus multiple fault diagnosis is a challenging field particularly in the control of large scale complex systems that can be viewed as hybrid systems. The main reason is that multiple faults are har...

The degradation of most eukaryotic mRNAs is initiated by removal of the poly(A) tail, and the major deadenylase activity is associated with the CCR4/CAF1/NOT complex (NOT complex). We here study the role of CNOT10, a protein that is found in human and trypanosome, but not in yeast, NOT complexes. Trypanosome (Tb) CNOT10 is essential for growth. TbCNOT10 interacted with the deadenylase TbCAF1 an...

A hybrid approach for intrusion detection in computer networks is presented in this paper. The proposed approach combines an evolutionary-based fuzzy system with an Ant Colony Optimization procedure to generate high-quality fuzzy-classification rules. We applied our hybrid learning approach to network security and validated it using the DARPA KDD-Cup99 benchmark data set. The results indicate t...

Organic-inorganic hybrid nanoflowers, a newly developed class of flower-like hybrid nanoparticles, have received much attention due to their simple synthesis, high efficiency, and enzyme stabilizing ability. This article covers, in detail, the types, structural features, mechanism of formation, and bio-related applications of hybrid nanoflowers. The five major types of hybrid nanoflowers are di...

The direct interaction of the Escherichia coli cytotoxin RelE with its specific antidote, RelB, was demonstrated in two ways: (i) copurification of the two proteins and (ii) a positive yeast two-hybrid assay involving the relB and relE genes. In addition, the purified RelE protein exhibited ribosome-binding activity in an in vitro assay, supporting previous observations suggesting that it is an...

4-tert-Octylphenol (4-t-OP) was treated with the white rot fungus Phanerochaete sordida YK-624 under ligninolytic condition with low-nitrogen and high-carbon culture medium. 4-t-OP completely disappeared after 5 days of treatment and the activities of ligninolytic enzymes, laccase and manganese peroxidase (MnP), were detected during this period, thus suggesting that the disappearance of 4-t-OP ...