نتایج جستجو برای: hvs i

تعداد نتایج: 1039825  

Journal: :Optics letters 2010
Ivan Moreno

Assessing how uniform the light distribution is throughout an illuminated target is important in many applications, but traditional methods do not quantify the variability of illuminance as the human visual system (HVS) does. Considering that most light patterns are intended for humans, I propose a simple metric that assesses the uniformity in a similar way as humans do. This uniformity indicat...

Journal: :The Journal of general virology 1989
R W Honess M A Craxton L Williams U A Gompels

We present the nucleotide sequence of a region from the genome of the A + T-rich gammaherpesvirus, herpesvirus saimiri (HVS), which includes the coding sequences for the viral thymidine kinase (TK) gene. The organization of genes in this region resembles the homologous region of the Epstein-Barr virus (EBV) genome and is very compact, using overlapping coding sequences and with nucleotides shar...

Journal: :Human biology 2000
M V Derenko B A Malyarchuk I K Dambueva G O Shaikhaev C M Dorzhu D D Nimaev I A Zakharov

The mtDNAs of 76 individuals representing the aboriginal populations of South Siberia, the Tuvinians and Buryats, were subjected to restriction fragment length polymorphism (RFLP) analysis and control region hypervariable segment I (HVS-I) sequencing, and the resulting data were combined with those available for other Siberian and East Asian populations and subjected to statistical and phylogen...

Journal: :Journal of virology 1996
E Cesarman R G Nador F Bai R A Bohenzky J J Russo P S Moore Y Chang D M Knowles

A new human herpesvirus was recently identified in all forms of Kaposi's sarcoma (Kaposi's sarcoma-associated herpesvirus [KSHV] or human herpesvirus 8), as well as in primary effusion (body cavity-based) lymphomas (PELs). A 12.3-kb-long KSHV clone was obtained from a PEL genomic library. Sequencing of this clone revealed extensive homology and colinearity with the right end of the herpesvirus ...

Journal: :Archives of medical research 2006
Mehdi Shafa Shariat Panahi Massoud Houshmand Abdol Reza Tabassi

BACKGROUND Leber hereditary optic neuropathy (LHON) is a maternally inherited form of retinal ganglion cell degeneration leading to optic atrophy in young adults. It is caused by three primary point mutations including G11778A, G3460A, and T14484C in the mitochondrial genome. These three mutations account for the majority of LHON cases and affect genes that encode for different subunits of mito...

2018
Jessica M. Hogestyn David J. Mock Margot Mayer-Proschel

Human herpesviruses (HVs) have developed ingenious mechanisms that enable them to traverse the defenses of the central nervous system (CNS). The ability of HVs to enter a state of latency, a defining characteristic of this viral family, allows them to persist in the human host indefinitely. As such, HVs represent the most frequently detected pathogens in the brain. Under constant immune pressur...

Journal: :Journal of virology 1998
J Guo K Williams S M Duboise L Alexander R Veazey J U Jung

STP-C488 (STP of herpesvirus saimiri [HVS] group C strain 488 [C488]) is the only virus-encoded protein found to associate with cellular ras and activate ras signal transduction pathways. To investigate an important role for ras signal transduction in STP-dependent growth transformation, we constructed recombinant strains of HVS C488 in which the STP-C488 oncogene was replaced with cellular nor...

Journal: :Human biology 2003
Olga Belyaeva Marina Bermisheva Andrey Khrunin Petr Slominsky Natalia Bebyakova Elza Khusnutdinova Alexei Mikulich Svetlana Limborska

The sequence of the first hypervariable segment (HVS-I) of mitochondrial DNA (mtDNA) was determined in 251 individuals from three eastern Slavonic populations, two Russian and one Belorussian. Within HVS-I, 78 polymorphic positions were revealed. Within-population diversity of HVS-I varies slightly among three samples; its estimates do not differ strongly from those for European populations. Ha...

2012
Kari R. Nations Roberta Bursi Peter Dogterom Larry Ereshefsky Lev Gertsik Tim Mant Jacques Schipper

BACKGROUND A key challenge to dose selection in early central nervous system (CNS) clinical drug development is that patient tolerability profiles often differ from those of healthy volunteers (HVs), yet HVs are the modal population for determining doses to be investigated in phase II trials. Without clear tolerability data from the target patient population, first efficacy trials may include d...

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