نتایج جستجو برای: human embryonic kidney cell line

تعداد نتایج: 3360588  

Ali Jahanian-Najafabadi Amaneh Mohammadi Roushandeh Golamhossein Hassanshahi Mehryar Habibi Roudkenar Parisa Bahmani Raheleh Halabian

Background: Heme oxygenase-1 (HO-1) is a cytoprotective and antiapoptotic enzyme, which has been involved in maintaining cellular homeostasis, and plays an important protective role by modulating oxidative injury. Up-regulation of (HO-1) has contributed to tumorogenicity of some cancers. In this study we investigated the expression pattern of the HO-1, in five different human-derived cancer cel...

Background: Recent researches have demonstrated that human T-cell immunoglobulin mucin 1 (TIM-1) glycoprotein plays important roles in regulation of autoimmune and allergic diseases, as well as in tumor immunity and response to viral infections. Therefore,targeting TIM-1 could be a potential therapeutic approach against such diseases. Objectives: In this study, we aimed to express TIM-1 protein...

ژورنال: پژوهش در پزشکی 2012
بهبهانی, ماندانا , فضیلتی, محمد, کاراپتیان, ژیرایر , گردانیان, بابک,

Abstract Background: Taking into account the resistance of cancer cells to chemical drugs and considering the various reports on the effects of plants from the genus Artemisia for the cure of various ailments and diseases, this investigation was undertaken to compare the cytotoxic effects of different plant organs collected from low and high altitudes. In this study the cytotoxicity of metha...

Journal: :research in pharmaceutical sciences 0
mina mirian razieh taghizadeh hossein khanahmad mansour salehi ali jahanian-najafabadi hojjat sadeghi-aliabadi

hepatitis b virus (hbv) is considered as a global health concern and hepatitis b surface antigen (hbsag) is the most immunogenic protein of hbv. the purpose of this study was to evaluate the expression of hbsag on the cell surface of human embryonic kidney cell line (hek293t). after transformation of expression vector pcdna/hbsag to e.coli top10f’, plasmid was extracted and digested with bglii....

Journal: :cell journal 0

objective: grape virus diseases are a serious problem in iran. leaves and fruits of grape have been used for different purposes like cooking in iran. the present investigation was carried out to study on the cytotoxic-activities of extracts of fruits and leaves of vitis vinifera from both virus-free and virus-infected grape cultivars against breast cancer cell line (mda-mb-231) and human embryo...

Journal: :Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 2013
Xinzi Lin Lin Qi Zhiguo Li Hao Chi Wanjun Lin Yan Wang Zesheng Jiang Mingxin Pan Yi Gao

OBJECTIVES The risk of porcine endogenous retrovirus infection is a major barrier for pig-to-human xenotransplant. Porcine endogenous retrovirus, present in porcine cells, can infect many human and nonhuman primate cells in vitro, but there is no evidence available about in vitro infection of human liver cells. We investigated the susceptibility of different human liver cells to porcine endogen...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه رازی - دانشکده علوم 1391

we have two part in this thesis, at first: the interaction of native calf thymus dna (ct-dna) with two anthraquinones including quinizarin (1,4- dihydroxy anthraquinone) and danthron (1,8- dihydroxy anthraquinone) in a mixture of 0.04 m brittone-robinson buffer and 50% of ethanol were studied at physiological ph by uv-vis absorption, florescence, circular dichroism spectroscopic methods, viscos...

Journal: :jundishapur journal of microbiology 0
mojtaba fattahi abdizadeh infectious and tropical diseases research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; department of virology, institute pasteur of iran, tehran, ir iran manoochehr makvandi infectious and tropical diseases research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; department of virology, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; infectious and tropical diseases research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran. tel: +98-6113738313, fax: +98-6113738313 alireza samarbafzadeh department of virology, ahvaz jundishapur university of medical sciences, ahvaz, ir iran kayhan azadmanesh department of virology, institute pasteur of iran, tehran, ir iran

conclusions according to the high functionality of the produced recombinant vector, it seems a good applicable tool for making an indicator cell line in subsequent basic and drug studies. results recombinant vector, pgl4ltr-luc, has expression levels of more than 50 folds compared to the control when co-transfected with the tax expressing vector into hek 293t cells. moreover, cells display more...

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