Two major trends in computing systems are the growth in high performance computing (HPC) with in particular an international exascale initiative, and big data with an accompanying cloud infrastructure of dramatic and increasing size and sophistication. In this paper, we study an approach to convergence for software and applications/algorithms and show what hardware architectures it suggests. We...

Background: In recent decade, human umbilical cord blood derived mesenchymal stem cells (hUCB-MSCs) provide enormous potential for appropriate cell therapy, but they have limited growth potential and cease to proliferate due to cellular senescence, so providing a strategy for increasing the stem cell survival is necessary.  Methods: In this investigation, MSCs characterized by flow cytome...

ingolipids (GSLs) from echinoderms, a series of studies on the isolation and structural elucidation of the GSLs from sea cucumber species have been performed in our laboratory. In the study of the GSLs of the sea cucumber Holothuria pervicax (Torafunamako in Japanese), we reported the isolation and structure of four new ganglioside molecular species. Continuing the preceding studies, the isolat...

parallel computing is a topic of interest for a broad scientific community since it facilitates many time-consuming algorithms in different application domains.in this paper, we introduce a novel platform for parallel computing by using mpi and openmp programming languages based on set of networked pcs. umzhpc is a free linux-based parallel computing infrastructure that has been developed to cr...

(ABSTRACT) Human Protein C (hPC) is a vitamin K-dependent serine protease that has a critical role in the naturally-occurring anticoagulant pathway. Upon activation of the zymogen by thrombin at the endothelial cell surface, the active form of hPC has anticoagulant activity in hemostasis due to its ability to inactivate factors Va and VIIIa. For biological activity, hPC requires several post-tr...

This study was undertaken to determine how human pancreatic cancer (HPC-4) cells transduced with the TNF-GFP fusion gene (TLG) alter the antitumor response of human monocytes in vitro and whether they could act as an antitumor vaccine. In our model, HPC-4 cells were transduced with retroviral vector harboring TLG gene and designated as HPC-4(TLG). The TLG protein expression was confirmed by Wes...

This paper aims to develop a numerical multiscale homogenization method for prediction of elasto-viscoplastic properties of a high performance concrete (HPC). The homogenization procedure is separated into two-levels according to the microstructure of the HPC: the mortar or matrix level and the concrete level. The elasto-viscoplastic behavior of individual microstructural phases of the matrix a...