Term and preterm labor are associated with increased fetal hypothalamic-pituitary-adrenal (HPA) activation and synthesis of prostaglandins (PGs) generated through the increased expression of prostaglandin H synthase-II (PGHS-II) in the placenta. Inhibition of PGHS-II has been advocated as a means of producing uterine tocolysis, but the effects of such treatment on fetal endocrine functions have...

[1] This paper evaluates geo-seasonal relationships in tropical deep convection using radar and infrared data from Tropical Rainfall Measuring Mission (TRMM), near tropopause thin clouds from Stratospheric Air and Gas Experiment (SAGE) II, water vapor and carbon monoxide (CO) from the Earth Observing System (EOS) Microwave Limb Sounder (MLS), and the tropopause temperature from National Center ...

introduction: glycoconjugates are a class of glycoproteins or glycolipids, their terminal sugars are responsible for cell-cell and/or cell-extracellular matrix interactions. aberrant glycosylation of these compounds are one of the most important aspects of cellular transformation, metastasis and escape of tumoral cells from immune system and resistance to antineoplastic drugs. recent studies sh...

....................................................................................................... 7 ABBREVIATIONS ............................................................................................. 9 INTRODUCTION ............................................................................................. 11 Neuronal plasticity ......................................................

Diabetes mellitus exerts metabolic stress on cells and it provokes a chronic increase in the long-term activity of the hypothalamus-pituitary-adrenocortical (HPA) axis, perhaps thereby contributing to insulin resistance. GLP-1 receptor (GLP-1R) agonists are pleiotropic hormones that not only affect glycaemic and metabolic control, but they also produce many other effects including activation of...

Phenylketonuria (PKU), with its associated hyperphenylalaninemia (HPA) and mental retardation, is a classic genetic disease and the first to have an identified chemical cause of impaired cognitive development. Treatment from birth with a low phenylalanine diet largely prevents the deviant cognitive phenotype by ameliorating HPA and is recognized as one of the first effective treatments of a gen...

[1] We examined the consistency of time series for stratospheric ozone obtained by ozonesondes, SAGE II, HALOE, and SBUV(/2) in the northern extratropics and find excellent agreement for interannual variability and trends of ozone for 50–12.5 hPa over Europe. Ozonesonde, SAGE, and HALOE data agree well for 200 hPa–12.5 hPa. Ozone in the past few years is 6% below values in the early 1980s for 8...

Background: Human platelet antigens (HPAs) are part of platelet GP complexes have the potential to contribute to the autoantibody production. Moreover, these antigens demonstrate different patterns of distribution on different ethnic groups and variation in some types of diseases. This study was objected to determine the incidence of HPA-1 to -5 and -15 polymorphisms in the Iranians suffering f...

DNA methylation has been correlated with reduced gene expression in a number of studies, although evidence for a casual link between the two events has been lacking. Because microinjection of simian virus 40 (SV40) DNA into the nucleus of Xenopus laevis oocytes results in the synthesis of both early and late viral gene products, it was possible to test whether a specific methylation event can a...