نتایج جستجو برای: hotspot analysis
تعداد نتایج: 2829932 فیلتر نتایج به سال:
MOTIVATION In many organisms, including humans, recombination clusters within recombination hotspots. The standard method for de novo detection of recombinants at hotspots is sperm typing. This relies on allele-specific PCR at single nucleotide polymorphisms. Designing allele-specific primers by hand is time-consuming. We have therefore written a package to support hotspot detection and analysi...
PURPOSE A computer-assisted microvessel analysis system was developed to evaluate correlations between the architecture of biopsy specimen microvessels and the outcome for patients with esophageal cancer treated with chemoradiotherapy. EXPERIMENTAL DESIGN Biopsy specimens from 51 patients with esophageal cancer (T(2-3), any N, M0) treated with chemoradiotherapy were immunostained with an anti...
This paper presents an approach of compact thermal modeling — HotSpot, which is parameterized according to design geometrical dimensions and material physical properties. While most existing compact thermal modeling methods facilitate thermal analysis of existing package designs, the HotSpot modeling method is more suitable for the exploration of new designs at both the die level and the packag...
A combination of two approaches, namely QTL analysis and gene enrichment analysis were used to identify candidate genes in the "QTL-hotspot" region for drought tolerance present on the Ca4 pseudomolecule in chickpea. In the first approach, a high-density bin map was developed using 53,223 single nucleotide polymorphisms (SNPs) identified in the recombinant inbred line (RIL) population of ICC 49...
Wi-Fi hotspots are becoming very popular. Due to limited costs, they are an effective solution to provide wireless Internet access to nomadic users. A key point to exploit the potentialities of Wi-Fi hotspots is managing the scarce energetic resources of mobile devices. To this end, the IEEE 802.11 standard defines a Power-Saving Mode aimed at reducing the energy consumption due to networking a...
The impact of somatic missense mutation on cancer etiology and progression is often difficult to interpret. One common approach for assessing the contribution of missense mutations in carcinogenesis is to identify genes mutated with statistically nonrandom frequencies. Even given the large number of sequenced cancer samples currently available, this approach remains underpowered to detect drive...
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