Bee venom is a complex substance which acts in different ways; local or systemic anaphylaxis associated with IgE and direct toxic effects of the large volume of injected venom. We report a 10- year-old boy who was the vulnerable of 5989 honey bee attacks. To the best of our knowledge, this case had the ultimate number of honey bee stings in the literature, until now. He was admitted to pediatri...

abstrac:    in recent years, honey bee products other than just honey such as pollen, propolis, waxes and venoms have gained considerable attention. hive is the most important tool in honey bee industry, the proper construction of which could play a key role in improving honey bee production.  since 1382, investigations have been done on hives made inside the country to eliminate deficiencies s...

severe allergic reactions during specific immunotherapy may occur in the treatment of hymenoptera sting allergy. the objective of the present study was to examine the characteristics of allergic reactions during specific immunotherapy in patients with allergy towards hymenoptera venom in the iranian population. a prospective study was performed using the clinical reports of 27 patients with ana...

For the past 10 years, beekeeping has increased due to a growing awareness of the disappearance of bees since Colony Collapse Disorder. Most of the disappearance of honey bees can be attributed to the use of pesticides. Apitherapy is the science and art of maintaining health with the use of products from the honeybee hive: honey, bee pollen, propolis, royal jelly, and bee venom. We have been be...

controversial immunomodulatory properties of bee venom (bv) have provided an appropriate field for more investigation. the aim of present research was to verify the effects of honeybee venom on matrix metalloproteinase activity and interferon production as well as cell proliferation in monocyte and fibroblast cell lines. the monocyte and fibroblast cell lines (k562, ht-1080, wehi-164) were used...

Stinging events involving honey bees and wasps are rare; most deaths or clinically important incidents involve very few stings (< 10) and anaphylactic shock. However, mass stinging events can prove life-threatening via the toxic action of the venom when injected in large amounts. With the advent of the Africanized honey bee in the southwestern United States and its potential for further spread,...

Bee venom from honey bees (Apis Mellifera L.) is known to have many pharmacological and biological properties. Melittin, a peptide consisting of 26 amino acids, as the main component bee venom. The study aims develop rapid capillary electrophoresis method for separating quantifying melittin in honeybee Since basic peptide, it will adhere wall during separation. Two different methods were develo...

One of the most widely used techniques for water content determination in food is Karl Fischer (KF) titration. Compared to other methods based on loss of weight, the primary advantage of the Karl Fischer titration method is its high selectivity to water. The aim of the study was to develop and validate the Karl Fischer method for moisture determination in pollen loads, royal jelly, bee venom an...

The venom of the European honey bee Apis mellifera is an intricate mixture of chemical compositions, including proteins, peptides, enzymes, and other small molecules. Lately, there has been growing interest in the use of melittin, due to its wide range of biological and potential therapeutic applications. Melittin, which is considered to be an antimicrobial, antitumor, and antiinflammatory pept...