purpose: to evaluate total plasma homocysteine level during the acute phase of central retinal vein occlusion (crvo) compared with a matched healthy group in iranian population, and determine whether hyperhomocysteinemia is also a risk factor for crvo. methods: a study group contains 54 patients presenting with crvo in recent one month, acute phase of the decease, was compared for fasting total...

the distribution of total plasma homocysteine concentrations in relation to the sex and age is described, in a population of shiraz, south west of iran and compared to those reported in other populations.  two hundred and one healthy males and 201 healthy females aged >15 y were randomly selected.  total plasma homocysteine concentrations were measured using high performance liquid chromatograp...

background: it is well documented that coronary artery bypass grafting (cabg) with cardiopulmonary bypass (cpb) causes ischemia and oxidative stress of the whole body. to compare the effect of on – pump and off –pump cabg on the induction of the oxidative stress and the metabolism of homocysteine which is involved in the synthesis of glutathione was investigated in the cabg patients during the ...

background: elevated level of plasma homocysteine has been related to various diseases. patients with hyperhomocysteinemia can develop hepatic steatosis and fibrosis. we hypothesized that oxidative stress induced by homocysteine might play an important role in pathogenesis of liver injury. also, the cellular response designed to combat oxidative stress is primarily controlled by the transcripti...

Background: Elevated level of plasma homocysteine has been related to various diseases. Patients with hyperhomocysteinemia can develop hepatic steatosis and fibrosis. We hypothesized that oxidative stress induced by homocysteine might play an important role in pathogenesis of liver injury. Also, the cellular response designed to combat oxidative stress is primarily controlled by the transcripti...

recent studies have documented the importance of lipids and lipoproteins as determinants of serum total homocysteine concentrations in persons with myocardial infarction, and in healthy subjects. associations between various biological systems and total homocysteine have also been reported. however, some of these associations are poorly understood. the purpose of our study was to measure serum ...

Background and Objectives: Type 2 diabetes is the most prevalent form of diabetes mellitus and is associated with a variety of complications. Homocysteine is an important independent risk factor for atherosclerotic diseases in both diabetic and non diabetic subjects. The association between these two is still unclear. The aim of this study was to assess the serum homocysteine levels in uncompli...

OBJECTIVE: Level of serum homocysteine is remarkably common among patients with moderate to sever renal failure. We assessed whether serum homocysteine concentrations were correlated with proteinuria in overt diabetic nephropathy. MATERIALS AND METHODS: A cross-sectional study was carried out on 45 patients (29 males, 16 females) with overt proteinuria. All subjects had type 2 diabetes. Data i...

Introduction: Homocysteine is an aminoacid yielded from methionin to cysteine metabolism. Normal plasma concentration of homocysteine in human is between 5-15 mol/l and an increase more than 5 mol/l can increase the risk of cardiovascular diseases, atherosclerosis and thrombosis. On the other hand in dialysis patients due to some reasons such as uremia, genetic factors, dialysis related factors...