نتایج جستجو برای: hk13
تعداد نتایج: 15 فیلتر نتایج به سال:
TO THE EDITOR Human tissue kallikreins are a family of 15 trypsin or chymotrypsin-like secreted serine proteases (kallikrein protein (hK1–hK15) found in a variety of tissues (Yousef and Diamandis, 2001). In the stratum corneum (SC), we previously quantified hK5, hK6, hK7, hK8, hK10, hK11, hK13, and hK14 as candidates of desquamation-related proteases and compared the hK levels among various age...
Human tissue kallikrein genes, located on the long arm of chromosome 19, are a subgroup of the serine protease family of proteolytic enzymes. Initially thought to consist of three members, the human kallikrein locus has now been extended and includes 15 tandemly located genes. These genes, and their protein products, share a high degree of homology and are expressed in a wide array of tissues, ...
TO THE EDITOR Peeling skin syndrome type B (PSS-type B, MIN 270300) is a congenital skin disease associated with continual skin peeling and ichthyotic erythroderma, known to display various clinical similarities with Netherton syndrome (NS, caused by genetic defects of serine protease inhibitor Kazal-type5 (SPINK5), MIN 256500) (Wile, 1924; Traupe, 1989; Magert et al., 1999; Chavanas et al., 20...
BACKGROUND The role of various proteases in the pathogenesis of Alzheimer's disease is well documented. Recently, many members of the human tissue kallikrein family, a group of 15 secreted serine proteases, were found to be highly expressed in the central nervous system (CNS). Some of these enzymes can be measured in cerebrospinal fluid (CSF) by using ELISA-type methodologies. METHODS We quan...
The polypeptide subunits of the 10 nm intermediate filaments (IFs) in epithelial cells can be grouped into two large multigene families, termed type I and type II cytokeratins (CKs) which are expressed in stoichiometrically equal amounts in a tissuespecific and cell type-restricted pattern (Fuchs and Weber, 1994; Moll, 1998). CK filaments (CKFs) are considered to be particularly important for e...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید