The Mycobacterium tuberculosis genome possesses homologues of the ruvC and yqgF genes that encode putative Holliday junction (HJ) resolvases. However, their gene expression profiles and enzymatic properties have not been experimentally defined. Here we report that expression of ruvC and yqgF is induced in response to DNA damage. Protein-DNA interaction assays with purified M. tuberculosis RuvC ...

Humulus japonicus Siebold & Zucc. (HJ) has traditionally been administered to patients with pulmonary disease, skin disease and hypertension in Korea, and it is considered to exert anti-inflammatory, antioxidant, antimicrobial and antimycobacterial effects. However, its effects against Alzheimer's disease (AD) have yet to be explored. Thus, this study was carried out to investigate whether HJ h...

Under the assumption of multivariate normality of asset returns, this paper presents a geometrical interpretation and the finite-sample distributions of the sample Hansen-Jagannathan (1991) bounds on the variance of admissible stochastic discount factors, with and without the nonnegativity constraint on the stochastic discount factors. In addition, since the sample Hansen-Jagannathan bounds can...

In this paper, we characterize holomorphic functions / such that the Hankel operators Hj are in the Schatten classes on bounded strongly pseudoconvex domains. It is proved that for p > In , Hj is in the Schatten class Sp if and only if / is in the Besov space Bp ; for p < In , Hj is in the Schatten class Sp if and only if / = constant.

We examined the effects of Hachimi-jio-gan (HJ) on the small intestinal function in streptozotocin (STZ)-induced diabetic rats. The rats had free access to pellets containing 1% HJ extract powder for 4 weeks after STZ administration. The intestinal disaccharidase (sucrase and maltase) activity was elevated in STZ-treated rats compared with control rats, whereas it was significantly reduced by H...

Intersection and measured intersection graphs are quite common in the literature. In this paper we introduce the analogous concept of measured difference graphs: Given an arbitrary hypergraph H = {H1, ..., Hn}, let us associate to it a graph on vertex set [n] = {1, 2, ..., n} in which (i, j) is an edge iff the corresponding sets Hi and Hj are “sufficiently different”. More precisely, given an i...

On September 6th, 2008, HJ-1A/B, which is a Micro-satellite Constellation for Environment and Disaster Monitoring, was successfully launched in China. HJ-1A/B is composed by two small satellites named as Satellite-A (HJ-1A) and Satellite-B (HJ-1B). The payloads of HJ-1A include a multispectral imager and an interferometric imaging spectrometer; the payloads of HJ-1B include an infrared scanner ...

We provide a variational derivation of the limit shape of minimal difference partitions and discuss the link with exclusion statistics. This paper is dedicated to Professor Leonid Pastur for his 70th anniversary. A partition of a natural integer E [1] is a decomposition of E as a sum of a nonincreasing sequence of positive integers {hj}, i.e., E = ∑ j hj such that hj ≥ hj+1, for j = 1, 2 . . .....

By using the Hamilton–Jacobi [HJ] framework, higher-order Maxwell–Chern–Simons theory is analyzed. The complete set of HJ Hamiltonians and a generalized differential are reported, from which all symmetries identified. In addition, we our study by performing Gitman–Lyakhovich–Tyutin [GLT] framework compare results both formalisms.

Holliday junction (HJ) resolvases are structure-specific endonucleases that cleave four-way DNA junctions (HJs) generated during DNA recombination and repair. Bacterial RuvC, a prototypical HJ resolvase, functions as homodimer and nicks DNA strands precisely across the junction point. To gain insights into the mechanisms underlying symmetrical strand cleavages by RuvC, we performed crystallogra...