نتایج جستجو برای: hiv infection of cd4 t cells
تعداد نتایج: 21478443 فیلتر نتایج به سال:
Background: Lymphocyte subsets enumeration is considered prominent in the management of primary and acquired immunodeficiency disorders. Because of local variations due to race, age, gender, and environmental conditions on lymphocyte subsets, and to improve the accuracy of interpretation of laboratory findings, reference intervals must be determined in every population. Objective: To establish ...
In this paper we consider a fractional order model of HIV infection of CD4+T cells and we transform this fractional order system of ordinary differential equations to a system of weakly singular integral equations. Afterwards we propose a Nystrom method for solving resulting system, convergence result and order of convergence is obtained by using conditions of existence and uniqueness of solut...
BACKGROUND CD4 T-cells expressing Foxp3 are expanded systemically during active tuberculosis (TB) regardless of HIV-1 co-infection. Foxp3+ CD4 T cells are targets of HIV-1 infection. However, expansion of HIV-1 infected Foxp3+ CD4 T cells at sites of HIV/TB co-infection, and whether they contribute to promotion of HIV-1 viral activity is not known. METHODS Pleural fluid mononuclear cells (PFM...
HIV-1 infection results in the progressive loss of CD4 T cells. In this study, we address how different pathogen-specific CD4 T cells are affected by HIV infection and the cellular parameters involved. We found striking differences in the depletion rates between CD4 T cells to two common opportunistic pathogens, cytomegalovirus (CMV) and Mycobacterium tuberculosis (MTB). CMV-specific CD4 T cell...
UNLABELLED CD4+ T cells play a pivotal role in the control of chronic viral infections. Recently, nontraditional CD4+ T cell functions beyond helper effects have been described, and a role for cytolytic CD4+ T cells in the control of HIV infection has been suggested. We define here the transcriptional, phenotypic, and functional profiles of HIV-specific cytolytic CD4+ T cells. Fluidigm BioMark ...
HCV infection has been hypothesized as a contributor of poor CD4+ recovery in patients living with HIV (PLWHIV). Aim this study was to evaluate CD4+, CD8+ cells and CD4/CD8 ratio trends before after treatment direct acting agents (DAA) PLWHIV. HIV/HCV enrolled ICONA HepaICONA cohorts HIV-RNA?50 copies/ml who achieved sustained viral response DAA were studied. A linear regression model used inve...
This paper presents a numerical method for solving a fractional model of HIV infection of CD4 + T cells. Using this model, we can examine the progression and spread of HIV. This method is a collocation method based on Dikson polynomials. Chebyshev's nodes are used in this method. By performing this process, the system of fractional differential equations converted to a nonlinear equations syst...
We examined the role of CD4(+) T cell IL-21 production in viral control of HIV infection. HIV-infected individuals had greater circulating IL-21-producing CD4(+) T cells in blood compared with uninfected volunteers. HIV-specific IL-21-producing CD4(+) T cells were detected in blood during untreated acute and chronic HIV infection, and elevated frequencies of these cells correlated with relative...
Latent HIV-1 infection of resting memory CD4(+) T cells represents the major barrier to HIV-1 eradication. To determine whether the CCR7 ligands involved in lymphocyte migration can alter HIV-1 infection of resting CD4(+) T cells, we infected purified resting CD4(+) T cells after incubation with the chemokines CCL19 and CCL21. Incubation with CCL19 or CCL21 did not alter markers of T-cell activ...
In this article, we present a fractional order HIV-1 infection model of CD4+ T-cell. We analyze the effect of the changing the average number of the viral particle N with initial conditions of the presented model. The Laplace Adomian decomposition method is applying to check the analytical solution of the problem. We obtain the solutions of the fractional order HIV-1 model in the form of infini...
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