نتایج جستجو برای: histone h1

تعداد نتایج: 54763  

2010
Hideharu Hashimoto Yasunari Takami Eiichiro Sonoda Tomohito Iwasaki Hidetomo Iwano Makoto Tachibana Shunichi Takeda Tatsuo Nakayama Hiroshi Kimura Yoichi Shinkai

In eukaryotic nuclei, DNA is wrapped around an octamer of core histones to form nucleosomes, and chromatin fibers are thought to be stabilized by linker histones of the H1 type. Higher eukaryotes express multiple variants of histone H1; chickens possess six H1 variants. Here, we generated and analyzed the phenotype of a complete deletion of histone H1 genes in chicken cells. The H1-null cells s...

2018
Carlos Contreras Minaya Villasana Michael J Hendzel Gustavo Carrero

Histones H1 or linker histones are highly dynamic proteins that diffuse throughout the cell nucleus and associate with chromatin (DNA and associated proteins). This binding interaction of histone H1 with the chromatin is thought to regulate chromatin organization and DNA accessibility to transcription factors and has been proven to involve a kinetic process characterized by a population that as...

2015
A. Kowalski J. Pałyga S. Knaga A. Witkowski

This work was aimed at comparing distribution of isoforms for polymorphic histone H1 variants H1.b and H1.z and variably abundant histone H1.d subtype between quail (Coturnix japonica) population selected for a high egg yolk cholesterol content and the control birds. The isoforms of histone H1.b (H1.b1, H1.b2) and histone H1.z (H1.z1, H1.z2) differed in their apparent molecular weights judging ...

Journal: :Nucleic acids research 1981
T Diez-Caballero F X Avilés A Albert

The interaction of calf thymus histone H1 with homologous and heterologous DNA has been studied at different ionic strengths. It has been found that about 0.5 M NaCl histone H1, and its fragments N-H1 (residues 1-72) and C-H1 (residues 73-C terminal), precipitate selectively a small fraction of calf thymus DNA. This selective precipitation is preserved up to very high values (less than 2.0) of ...

2018
Hao Zhang Tianhu Li

The data presented in this article are related to the research article entitled "Quantitative determination of linking number differences between circular polynucleosomes and histone H1-bound circular polynucleosomes" Zhang et al. (in press) [1]. DNA linking number differences between histone H1-free and histone H1-bound circular polynucleosomes at various spermidine concentrations was quantita...

Journal: :Transplant immunology 2007
Toshiaki Nakano Shigeru Goto Chia-Yun Lai Li-Wen Hsu Kazuhisa Ono Seiji Kawamoto Yu-Chun Lin Ying-Hsien Kao Kuei-Chen Chiang Naoya Ohmori Takeshi Goto Shuji Sato Chieh-Hsien Tu Bruno Jawan Yu-Fan Cheng Chao-Long Chen

BACKGROUND We recently reported that autoreactive antibody (Ab) against nuclear histone H1 had been identified as an immunosuppressive factor in a rat tolerogenic orthotopic liver transplantation (OLT) model. The present study aimed to determine whether the up-regulation of antihistone H1 Ab by histone H1 vaccination leads to tolerance. METHODS Histone H1-immunized rats were established by in...

2002
ANDRZEJ KOWALSKI JAN PAŁYGA EWA GÓRNICKA

Multiple non-allelic subtypes of histone H1 have been detected in higher organisms. These specific variants with distinct structural features may differ in their ability to condense chromatin and hence modify transcriptional activity. Such functional divergence between H1 subtypes has still not been established definitively, but it cannot be excluded that the role of a particular subtype may de...

2011
ISHTIAQ AHMAD WAQAR AHMAD

Linker histone H1 belongs to the family of proteins that are involved in organizing eukaryotic DNA into a compact structure. Many types of linker histone H1 are found in mammals; and the subtypes are cell specific and their amount in different types of cells varies according to the cell functions. Post-translational modifications occur on different amino acids in each subtype of linker histone ...

Journal: :Molecular immunology 2005
Li-Wen Hsu Shigeru Goto Toshiaki Nakano Chia-Yun Lai Ying-Hsien Kao Yu-Chun Lin Seiji Kawamoto Kazuhisa Ono Roger Lord Takeshi Goto Naoya Omori Shuji Sato Kuei-Chen Chiang Shu-Hui Chen Bruno Jawan Yu-Fan Cheng King-Wah Chiu Chao-Long Chen

We previously demonstrated the immunosuppressive activity of anti-histone H1 autoreactive antibodies (Ab) transiently induced in serum of a rat tolerogenic orthotopic liver transplantation (OLT) model. In the present study, we investigated the effects of anti-histone H1 Ab on dendritic cells (DCs), T-cells, lymphokine-activated killer (LAK) cells, and human natural killer (NK) cells. The effect...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید