Histiocytosis, according to Histiocyte Society2, is traditionally classifi ed into three main groups: Class I: (Langerhans cell histiocytosis), formerly called X histiocytosis Class II: Histiocytosis of other mononuclear phagocytes different from Langerhans cells Class III: Histiocytic malignancies.1,3,4 Nevertheless, Langerhans cell Histiocytosis is the currently preferred term. It is classifi...

conclusions pericardial effusion was a rare finding in this case of langerhans cell histiocytosis. pericardial effusion in langerhans cell histiocytosis, which is an unusual presentation, should be considered when the patient experiences respiratory distress. introduction langerhans cell histiocytosis (lch) is a proliferative disorder of histiocytes in multiple organs. langerhans cell histiocyt...

During the past 40 years, three previously unrecognized disorders of the reticuloendothelial system have been described : Letterer-Siwe’s disease,’ Hand-Sch#{252}ller-Christian’s disease,24 and eosinophilic granuloma.5’6 Due largely to the influence of Lichtenstein,7 the opinion now prevails that these three disorders are fundamentally related. They differ from one another mainly in terms of pa...

Two young patients presented with generalised lymphadenopathy, otorrhoea, otitis, and rash. Over the next few years chronically discharging sinuses began to form over enlarged nodes and histological appearances were typical of histiocytosis X. In neither case were micro-organisms isolated from the lesions, and in both patients healing occurred with immunosuppressive agents. Chronic dermal sinus...

A case report of histiocytosis X in a 2 years old in­faut, primarily admitted a for jaundice is discussed. Major clinical manifestations included: Jaundice, bi­lateral otitis media. pallor and loss of weight. Clinical examination revealed hepatosplenomegaly. lymphadenopathies and sever anemia. Seborrr.eic eruptions and ptechias appeared over the scalp and other parts of body surface a few days ...