BACKGROUND Myopia is a leading cause of preventable blindness. Although, multiple cross-sectional epidemiological studies have confirmed that there is a high prevalence of myopia in high school-aged students in China. However, few longitudinal studies have been performed to assess junior high school students. In the present study, we investigate changes in the prevalence of myopia in third year...

PURPOSE To estimate the sibling recurrence risk (KS) and the sibling recurrence risk ratio (lambda(S)) for high myopia in a cohort in the United Kingdom. METHOD The recurrence risks for myopia and high myopia were estimated in the siblings of 296 randomly selected high myopes ascertained from an optometric practice population. A model using an age of onset of spectacle wear for myopia of 9.1 ...

PURPOSE To compare the posterior corneal curvature changes, in terms of corneal power and asphercity, following Refractive Small Incision Lenticule Extraction (ReLEx SMILE) procedure for low, moderate, and high myopia. METHODS This retrospective, non randomized, comparative, interventional trial; included 52 eyes of 26 patients, divided in three groups: low myopia (myopia ≤3 D [diopters] sphe...

High myopia is one of the leading causes of blindness worldwide. However, the exact etiology of high myopia remains unraveled despite numerous attempts of elucidation. Previous genome-wide association study (GWAS) has revealed that four single nucleotide polymorphisms (SNPs), including rs2969180, rs1652333, rs9307551, and rs7837791, were associated with high myopia in Caucasians. The present st...

PURPOSE To estimate gender- and age-specific prevalence of myopia and identify risk indicators for myopia in a population-based sample of Latino adults aged 40 years and older in La Puente, California. METHODS Noncycloplegic automated refraction with supplemental standardized subjective refraction was performed for presenting visual acuity worse than 20/20. Potential risk indicators for myopi...

purpose : to evaluate the efficacy, safety, predictability and stability of implantable collamer lens (icl) and toric icl for the treat­ment of high myopia and high myopic astigmatism methods : in this prospective nonrandomized clinical trial, 95 eyes of 51 patients who underwent icl (31 eyes) and toric icl (64 eyes) implantations were participate in eye research center, department of ophthalmo...

PURPOSE High myopia or pathological myopia is a common refractive error. Individuals with high myopia are subject to increased risk of serious eye complications. Accumulating evidence has demonstrated the role for heritability in ocular growth and in the development of high myopia. Retinoic acid and retinoic acid receptors play important roles in ocular development and in experimentally induced...

AIMS To report success in the treatment of high myopia in children with LASIK. To report the visual results, complications and postoperative management of children with high myopia. METHODS Six children (seven eyes) with high myopia were included in this series. Preoperative and postoperative refraction, visual acuity, and pachymetry were compared. RESULTS Six children with high myopia rang...

PURPOSE Examine the prevalence of myopia and high myopia, at 6 and 9 months postterm and 2 and 3 years postnatal in preterm children with birth weights < 1251 g who developed high-risk prethreshold retinopathy of prematurity (ROP) in the neonatal period and participated in the Early Treatment for ROP Study. DESIGN Randomized controlled clinical trial. PARTICIPANTS Four hundred one infants w...

OBJECTIVE To identify the genetic locus for X-linked nonsyndromic high myopia in a large Chinese family. METHODS Phenotypic information and DNA samples were collected from 19 individuals in a Chinese family; 7 had high myopia and 12 were unaffected. We performed a linkage scan on the X chromosome and sequenced several candidate genes. RESULTS High myopia in this family, presenting since ear...