UNLABELLED Manganese plays an important role in the cellular physiology and metabolism of bacterial species, including the human pathogen Vibrio cholerae The intracellular level of manganese ions is controlled through coordinated regulation of the import and export of this element. We have identified a putative manganese exporter (VC0022), named mneA (manganese exporter A), which is highly cons...

Two experimental high strength steel weld metals were produced with 7 wt-% nickel and either 2 or 0.5 wt-% manganese. Neural network predictions that it is advantageous to reduce the manganese concentration in high nickel alloys have been confirmed, with impact energy increasing from 32 to 113 J at –40uC. High resolution microstructural investigations showed that both weld metals contained main...

Concerns exist as to whether individuals may be at greater risk for neurotoxicity following increased manganese (Mn) oral intake. The goals of this study were to determine the equivalence of 3 methods of oral exposure and the rate (mg Mn/kg/day) of exposure. Adult male rats were allocated to control diet (10 ppm), high manganese diet (200 ppm), manganese-supplemented drinking water, and mangane...

Analysis of data obtained from the national hydrochemical survey show that about 42% of tubewells have manganese concentrations exceeding the WHO health-based guideline value of 0.4 mg/l. High manganese concentrations in groundwater have been found in the central, northern, and western regions of Bangladesh; groundwater in the north-eastern region of Bangladesh contain relatively less manganese...

BACKGROUND Neurotoxicity and pulmonary dysfunction are well-recognized problems associated with prolonged human exposure to high concentrations of airborne manganese. Surprisingly, histological characterization of pulmonary responses induced by manganese remains incomplete. The primary objective of this study was to characterize histologic changes in the monkey respiratory tract following manga...

The removal of manganese and humic acid (HA) by two nanofiltration membranes, TFC-SR2 and TFC-SR3, was investigated in order to highlight the influence of speciation on manganese and HA retention. Manganese speciation and complexation with HA were modelled to understand how speciation could affect NF removal mechanisms. The behaviour of the two membranes was drastically different for manganese ...

Two experimental high strength steel weld metals were produced with 7 wt. % nickel and manganese at 2 or 0.5 wt. %. Neural network predictions that Mn reductions increase toughness were confirmed with impact energy increasing from 32 to 113 J at –40 °C. High resolution microstructural investigations showed that both weld metals contained mainly martensite at interdendritic regions and predomina...

Manganese and ADHD A study published in Neurotoxicology has generated discussion because it shows a link between high levels of manganese (Mn) given to rats during infancy and the development of behavioral problems similar to Attention Deficit Hyperactivity Disorder. Mn is an essential element and is currently required by law in infant formulas, but can be neurotoxic at high levels. Recent repo...