BACKGROUND Hidradenitis suppurativa is a chronic, inflammatory, scarring disease characterized by recurrent flares. Recently, a group of 'autoinflammatory disorders' has been described. These disorders are characterized by recurrent inflammatory episodes not mediated by autoantibodies or antigen-specific T-cells. Some of these autoinflammatory disorders have been successfully treated with anti-...

Marjolin's Ulcer in Chronic Hidradenitis Suppurativa TO THE EDITOR: Hidradenitis suppurativa is a chronic inflammatory disease of the apocrine glands that most commonly involves the perianal, perineal, axillary, and inframammary regions. The etiology is poorly understood, with a genetic component, hormonal influence, and obesity being linked to the expression. Characteristic findings include di...

We report a girl with premature adrenarche, in whom the presenting feature was hidradenitis suppurativa. This association lends support to the view that hidradenitis suppurativa is an androgen-dependent disorder.

Background: Hidradenitis suppurativa is a chronic follicular occlusive disease in apocrine gland-bearing regions. Frequently refractory to conventional oral and topical treatments, it may require surgical intervention. Objective: To investigate the effectiveness of radiation therapy for refractory hidradenitis suppurativa. Methods and materials: Five patients with refractory Hurley stage II/III...

BACKGROUND The clinical improvement of hidradenitis suppurativa reported in a small number of patients with antitumour necrosis factor (anti-TNF)-alpha therapies supports the hypothesis for an altered immune response in these patients. OBJECTIVES To evaluate the state of the innate and adaptive immune responses in patients with hidradenitis suppurativa. METHODS Fifty-three patients and six ...

Hidradenitis suppurativa is a chronic inflammatory disease of the sweat glands and hair follicles which is rarely associated with squamous cell carcinoma (SCC). A case of vulval SCC complicating hidradenitis suppurativa is presented. In addition to being the first case to report the association of vulval SCC and hidradenitis suppurativa in the English language literature, it also illustrates th...

Hidradenitis suppurativa affects apocrine gland-bearing areas of skin and may produce perianal lesions clinically indistinguishable from the cutaneous manifestations of Crohn’s disease1, suggesting an association between the two diseases1–3. A recent histological study3 of hidradenitis suppurativa described epithelioid granulomas in 10 per cent of cases. Some of these patients had systemic gran...

INTRODUCTION Hidradenitis suppurativa of the groin is a chronic, relapsing inflammatory disease of the skin and subcutaneous tissues. Radical surgical excision is the treatment of choice. Often split-skin grafting or wound healing by secondary intention are used for defect closure, sometimes with disfiguring results. We describe our experience with radical excision of localised inguinal hidrade...

Hidradenitis suppurativa is an uncommon chronic suppurative inflammatory disease affecting the apocrine glands of the axillary and anogenital regions. Chronic recurrences of the disease can result in painful abscesses, sinus track and fistula formation, and disabling scarring in the affected areas. To our knowledge, hidradenitis suppurativa has not been reported previously in the radiology lite...

Hidradenitis suppurativa is a cutaneous, chronic, recurrent inflammatory disease. Here, we report the case of a 66-year-old man who had hidradenitis suppurativa in the buttocks. He suffered from diabetes mellitus. In the past, he had perianal abscesses. Because of improper treatment of furuncle infections in the buttocks, skin ulcers formed, which worsened and resulted in multiple fistulas. The...