The hexane-1,6-diammonium cation of the title compound, C(6)H(18)N(2) (2+)·2NO(3) (-), lies across a crystallographic inversion centre and shows significant deviation from planarity in the hydro-carbon chain. This is evident from the torsion angle of -64.0°(2) along the N-C-C-C bond and thse torsion angle of -67.1°(2) along the C-C-C-C bonds. An intricate three-dimensional hydrogen-bonding netw...

CONTEXT Scyphiphora hydrophyllacea is a shrub mangrove plant of the family Rubiaceae and not yet been studied for anti-hepatocarcinogenic effects. OBJECTIVES We investigated possible in vitro anti-hepatocarcinogenic and antioxidant properties of S. hydrophyllacea. MATERIALS AND METHODS Dried leaves of S. hydrophyllacea were sequentially extracted into hexane, chloroform, ethyl acetate, and ...

In this study, the 4-week oral toxicity and anti-cancer activity of the hexane layer of Melia azedarach L. var. japonica Makino's bark extract were investigated. We carried out a hollow fiber (HF) assay and 28- day repeated toxicity study to confirm the anti-cancer effect and safety of the hexane layer. The HF assay was carried out using an A549 human adenocarcinoma cell via intraperitoneal (IP...

± S.E.)6) was chromatographed on a silica gel colurnn to separate it into the 100% hexane, 20% AcOEtl hexane, 50% AcOEtlhexane and 100% AcOEt frs. The bioassay results clearly confirmed that the active component(s) in the original hexane fr. were concentrated in the 20% AcOEtfhexane fr. (92,4%± 1.6). The activities of the other frs. were as follows: 100% hexane fr. (O.O%± O.O), 50% AcOEt!hexane...

A detailed characterization of the microemulsion composition is necessary to make the phosphorimetry suitable as powerful analytical methodology. Four microemulsion systems (hexane/n-butanol/SDS/water, hexane/n-pentanol/SDS/water, hexane/3-pentanol/SDS/ water, and hexane/n-hexanol/SDS/water) were studied, establishing the oil/water (O/W) microemulsion composition with best phosphorimetric chara...

IN AN EARLIER STUDY (Barr et al., 1981) we explored the pathogenesis of soft-tissue necrosis induced in guinea-pigs by the concrolled extravascular administration of cytotoxic drugs. This system provides a model of the phenomenon which may complicate the inadvertent perivenous injection of cancer chemotherapeutic agents in clinical practice. The current investigation was undertaken in order to ...