Complexes of Mn(II) with 1,8-naphthyride containing amide group ligands 2-amino1-8,naphthyride-3-carboxamide (ANC), 2-amino-N-phenyl-1,8-naphthyride-3-carboxamide (APNC), 2-amino-N-(p-methyl phenyl)-1,8-naphthyridine-3-carboxamide(AMPNC), 2-amino-N-)p-bromo phenyl)1,8-naphthyridine-3-carboxamide(ABPNC), 2-amino-N-(p-chloro phenyl)-1,8-naphthyridine3-carboxamide (ACPNC), 2-amino-N-(p-methoxy phe...

A series of new hexahydroquinoline and 1,4-dihydropyrimidine derivatives were synthesized. Condensation of 2-methyl- thiazole-4-carboxaldehyde (1) with 1,3-cyclohexanedione and alkyl 3- aminocrotonate afforded 4-(2-methyl-thiazol-4-yl)-hexahydroquinoline while condensation of aldehyde (1) with benzoyl acetone and thiourea gave 1,4-dihydropyrimidine derivatives. The stereochemistry of 1,4-dihydr...

Staphylococcus aureus causes a wide variety of infections worldwide. Methicillin-resistant S. aureus is one of most common causes of nosocomial and community acquired infections. The fluoroquinolones are an important class of antibiotics that used to treat infections caused by S. aureus. Today, a significant increase in the rate of ciprofloxacin resistance in methicillin-resistant S. aureus str...

a series of new hexahydroquinoline and 1,4-dihydropyrimidine derivatives were synthesized. condensation of 2-methyl- thiazole-4-carboxaldehyde (1) with 1,3-cyclohexanedione and alkyl 3- aminocrotonate afforded 4-(2-methyl-thiazol-4-yl)-hexahydroquinoline while condensation of aldehyde (1) with benzoyl acetone and thiourea gave 1,4-dihydropyrimidine derivatives. the stereochemistry of 1,4-dihydr...

In the crystal structure of the title compound, C(6)H(5)ClN(2)O, the dihedral angle between the pyridine ring and the carboxamine group is 63.88 (8)°. Inter-molecular N-H⋯N and N-H⋯O hydrogen bonds link the mol-ecules into a two-dimensional network.

Herein, we report a new method of synthesis N-acylureas (E1–5) via reaction dibenzoylhydrazine carboxamide (N,2-bis(4-methoxybenzoyl)hydrazine-1-carboxamide) (C) and various benzylamines. Preparation was performed by the treatment 5,6-diaryl-3-methylthio-1,2,4-triazine (B) with Oxone which leads to oxidation triazine ring cleavage in high yield (82%). Five benzylamine derivatives containing dif...