Bioluminescence imaging has shown great potential for studying and monitoring disease progression in small animal pre-clinical imaging. However, absolute bioluminescence source recovery through tomographic multi-wavelength measurements is often hindered through the lack of quantitative accuracy and suffers from both poor localisation and quantitative recovery. In this work a method to incorpora...

In the present paper, we estimated backscattering factors for the TLD and active personal dosimeters using 662 keV gamma-ray photons on a PMMA surface, which are, for the TLD, 1.12; Dosicard, 1.116; DRD, 0.99; and Saphydose, 1.073, and on a water slab phantom surface; for the TLD, 1.115; Dosicard, 1.112; DRD, 1; and Saphydose, 1.059. The backscattering factor contribution for the Saphydose is n...

In the past the operational quantity H(p)(3) has been defined for calibration purposes in a slab phantom. Recently, an additional phantom in the form of a cylinder was suggested for eye lens dosimetry as a cylinder much better approximates the shape of a head than a slab. Therefore, this work investigates whether the quantity H(p)(3), when defined in the respective calibration phantom, adequate...

A new grid-based Boltzmann equation solver, Acuros, was developed specifically for performing accurate and rapid radiotherapy dose calculations. In this study we benchmarked its performance against Monte Carlo for 6 and 18 MV photon beams in heterogeneous media. Acuros solves the coupled Boltzmann transport equations for neutral and charged particles on a locally adaptive Cartesian grid. The Ac...

introduction: multiple fields and presence of heterogeneities create complex dose distributions that need three dimensional dosimetry. in this work, we investigated mr-based magic gel dosimetry as a three-dimensional dosimetry technique to measure the delivered dose to bladder and rectum in prostate radiation therapy. materials and methods: a heterogeneous slab phantom including bones was made....

Introduction: Multiple fields and presence of heterogeneities create complex dose distributions that need three dimensional dosimetry. In this work, we investigated MR-based MAGIC gel dosimetry as a three-dimensional dosimetry technique to measure the delivered dose to bladder and rectum in prostate radiation therapy. Materials and Methods: A heterogeneous slab phantom including bones was made....

The purpose of this study is to compare performance of several dosimetric meth-ods in heterogeneous phantoms irradiated by 6 and 18 MV beams. Monte Carlo (MC) calculations were used, along with two versions of Acuros XB, anisotropic analytical algorithm (AAA), EBT2 film, and MOSkin dosimeters. Percent depth doses (PDD) were calculated and measured in three heterogeneous phantoms. The first two ...

Telecobalt machine is one of the essential equipment needed in many cancer centers and still prominently used for the treatment of a variety of cancer cases in developing countries. This study aims to evaluate the impact of tissue heterogeneity corrections on 3D treatment planning system (Prowess). The human body contains a variety of tissues and cavities which vary widely in their physical and...

Introduction: In vitro dosimetric verification prior to patient treatment plays a key role in accurate and precision radiotherapy treatment delivery. Since the human body is a heterogeneous medium, the aim of this study was to design a heterogeneous pelvic phantom for radiotherapy quality assurance. Material and Methods: A pelvic phantom was ...