Background and Objectives: Meningoencephalitis in Iranian children is frequent, but encephalitis is rare .The frequency of HHV-6 and HHV-7 in central nervous system diseases of our children is unclear. The aim of this study was searching the DNA-s of HHV-6 & HHV-7 in CSF samples of children with meningoencephalitis  Materials and Methods: A cross sectional study (2007-2009) was done in Pediatr...

background: oncolytic herpes simplex virus (ohsv) vectors lacking γ34.5 has demonstrated anticancer effects without affecting normal cells. therefore, they are considered as ideal templates to construct efficient vectors for tumor targeting and cancer gene therapy. herein, we reported construction of three single/dually-labeled recombinant hsv-1 vectors, which provide an opportunity to replace ...

Molecular Medicine is a fairly multifaceted activity and according to various experiences of almost 30 years professional practice, it has been possible incorporate some molecular biotools in the study disease-causing pathogens both humans small animals relation latter, associated with canine herpes virus or distemper virus. However, André Lwoff: Viruses are viruses, so their detection does not...

Objective(s) The aim of this study was to search for new antiviral agents from herbal medicines. Ethanol extracts of C. semipervirens, C. semipervirens var. horizontalis and C. semipervirens cv. Cereiformis were used in experiments to test their influence on herpes viruses (HSV-1). Materials and Methods HeLa cells monolayers were infected with herpes viruses (HSV-1). Antiviral activity of th...

Despite great advances in solid organ transplantation (SOT) in recent decades, infection remains a major cause of morbidity and mortality among SOT recipients. Members of the herpesvirus family are the most common viral pathogens causing disease in this patient population. Herpes viruses are large enveloped DNA viruses that commonly reactivate during periods of severe immunosuppression. Current...

In addition to the bloodborne pathogens (BBPs) — human immunodeficiency virus (HIV) and hepatitis B and C viruses (HBV and HCV) — other viruses of concern in the dental office include rubella, mumps and measles viruses; the herpes viruses (herpes simplex virus [HSV] types 1 and 2, varicella-zoster, Epstein-Barr virus [EBV], cytomega lovirus and human herpes virus 6); human papilloma viruses; ad...

It has been proposed that intervertebral disc degeneration might be caused by low-grade infection. The purpose of the present study was to assess the incidence of herpes viruses in intervertebral disc specimens from patients with lumbar disc herniation. A polymerase chain reaction based assay was applied to screen for the DNA of eight different herpes viruses in 16 patients and two controls. DN...