the effect of different levels of wood betony (wb), stachys lavandulifolia extract, as complement in feed, on the performance of common carp, cyprinus carpio was evaluated. the fish (44±0.62 g) was assigned to four treatments, three replicates each. the fish was fed on normal diet with no wb (control) vs. diet containing 2, 4 and 8% of wb extract. fish were successively fed on the diet, 2% live...

The popular use of herbal products in the general community raises concerns for potential herb– drug interactions. The risk of herb–drug interactions is increased if the herbal medicines are used concurrently with drugs which have a narrow therapeutic range, or are used in certain groups of patients, such as the elderly or those with impaired liver and renal functions. This short paper reviews ...

Purpose Individuals using herbal medicines concomitantly with prescription drugs are at risk of harms due to herb-drug interactions. As part of a prospective active surveillance study to identify natural health product harms, a tool to identify herb-drug interactions was created for clinician use. Such tools require regular updating to remain clinically relevant. Our objective was to review the...

Though many studies have been performed to elucidate molecular mechanism of traditional Chinese medicines (TCMs) by identifying protein-compound interactions, no systematic analysis at herb level was reported. TCMs are prescribed by herbs and all compounds from a certain herb should be considered as a whole, thus studies at herb level may provide comprehensive understanding of TCMs. Here, we pr...

Herb-herb combinations have been used in Chinese medicine practice for thousands of years, yet scientific evidence of their therapeutic benefits is lacking. With increasing interest in shifting from the one-drug-one-target paradigm to combination therapy or polypharmacy to achieve therapeutic benefits for a number of diseases, there is momentum to explore new knowledge by tapping the past empir...

The main effects and interactions of four different mineral N levels (0, 50, 100 and 150kg fed -1 ) and four various poultry manure rates (0, 10, 15 and 20m 3 fed -1 ) on the vegetative growth, flowering, volatile oil content and chemical composition of marigold plants (Tagetes minuta) were investigated through two field experiments in 2000/2001 and 2001/2002. The obtained results, obviously, s...

More than ten percent of people suffer from at least one episode of depression and related mental disorders in a lifetime, and depression and related mental disorders are one of the world's greatest public health problems. A multiple system theory holds that dysregulation of the multiple systems underlies the pathogenesis of depression and related mental disorders, and new therapies based on th...

We investigated the effect of retinoic acid (RA) and herbimycin A (herb-A) on cell growth, cell differentiation, and colony formation of human neuroblastoma cell lines. The neuroblastoma line SK-N-SH expressed both neuroblast and nonneuronal phenotypes, whereas its subclone SH-SY5Y and the Kelly cell line were predominantly neuroblastic. Both herb-A and RA, given alone, moderately reduced cell ...