Background: The transmission of pathogens via blood transfusion is still a major threat. Expert conferences established the need for a pro-active approach and concluded that the introduction of a pathogen inactivation/reduction technology requires a thorough safety profile, a comprehensive pre-clinical and clinical development and an ongoing hemovigilance program. Material and Methods: The INTE...

Background: Patients with thalassemia major require frequent blood transfusions. Blood transfusion can lead to the adverse reactions. Reporting and evaluating the transfusion reactions are among the goals of implementing the hemovigilance system to improve blood recipients’ safety. This study aimed to compare the transfusion reactions in the thalassemia patients before and after implementation ...

BACKGROUND In recent years, pulmonary transfusion reactions have gained increasing importance as serious adverse transfusion events. METHODS Review of the literature. RESULTS Pulmonary transfusion reactions are not extremely rare and, according to hemovigilance data, important causes of transfusion-induced major morbidity and death. They can be classified as primary with predominant pulmona...

OBJECTIVES To report 2-years experience of using transfusion-related quality indicators as a tool in hemovigilance system implementation.  METHODS The study was carried out between 2012 and 2013. Blood transfusion service data were prospectively collected at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Donor reactions, transfusion reactions, fresh frozen plasma (FFP) in-date wast...

Neither screening method completely detects all clinically relevant bacterial contaminations. The effect of sampling time and volume as well as standardization of the assay applied has also to be taken into account. Therefore, minimizing the risk of contamination during manufacture by measures such as donor selection, skin disinfection, division, and processing within closed systems remains cru...

background: in spite of being vital to save the patients' life, blood transition may be dangerous and even fatal, too the aim of this study was to investigate the side effects (complications) of blood transfusion in the educational hospitals of qazvin. m aterials and methods: this is a descriptive cross sectional and practical study that was carried out in 2010. in this study, all the patients ...