background: hemorrhagic transformation (ht) of ischemic stroke (is) is a detrimental complication. this study investigated the association between serum ferritin level and ht in patients with massive is of middle cerebral artery.   methods: thirty patients with massive is of middle cerebral artery were enrolled in this prospective cohort study. they were divided into two groups based on the ser...

Background: Among different mechanisms, oxidative stress has a possible role in neural injury in cerebrovascular events. Objectives: Assessment the oxidants-antioxidants imbalance in ischemic and hemorrhagic strokes. Materials and Methods: Serum level of malondialdehyde, the main marker of lipid peroxidation, and total antioxidant capacity were measured in a group of 48 stroke patients consis...

background and aims: crimean-congo hemorrhagic fever (cchf) is a fatal viral disease that occurs in approximately 30 countries. it has the most extensive geographic range among the tick-borne viruses that affect human health. cchf viruses have a tripartite rna genome consisting of large (l), medium (m) and small (s) segments. this study was undertaken to determine the genetic relationship of cc...

conclusions our results showed that the study population perceived a high likelihood of cchf risk. improving public knowledge and awareness could result in a more realistic assessment of cchf risk, hence better compliance with taking precaution measures to tackle the disease. results approximately 70% of the respondents reported the cchf risk to be 'high'. factors independently associated with ...

background crimean-congo hemorrhagic fever (cchf) is a tick-borne disease caused by arbovirus which can be transmitted to human by several routes. tick bite and living in a rural area have been the most common factors for inception of cchf in adults and children in studies reported from iran. objectives this study was conducted to detect the disease acquisition routes among children with confir...

southeast of iran is an endemic area for malaria and crimean-congo hemorrhagic fever ( cchf). in 1999, we faced with an outbreak of cchf in sistan and baluchistan province, in the border of paki­stan and afghanistan. the most cases of malaria in iran are also reported from this area. this arti­cle presents a 17-year- old woman who admitted to our hospital because of acute fever, head­ache, epis...

context crimean-congo hemorrhagic fever (cchf) is a fatal viral disease which has 30% to 80% mortality rate. in endemic areas, livestock handlers, skin processors, veterinary staff, livestock market employees, farmers, and health care staff are at risk. diagnosis is made based on clinical manifestations, epidemiologic factors, and laboratory tests. here, we reviewed the epidemiology, clinical m...

Objective: To evaluate low-molecular-weight (LMW) DNA as possible prognostic biomarker in acute ischemic and hemorrhagic stroke. Methods:  LMW DNA samples were isolated from plasma and cerebrospinal fluid by phenol deproteinization, analyzed by gradient polyacrylamide electrophoresis and quantified by spectrophotometry. Results: Two common types of the stroke, ischemic and hemorrhagic, differ...