© Japi • January 2014 • Vol. 62  9 I n o r m a l h u m a n e r y t h r o c y t e s , HbA comprises > 90% of the total haemoglobin. Besides HbA, human erythrocytes contain other haemoglobin components that are of considerable interest. Some of these, such as HbA2 and foetal haemoglobin (HbF), like s i c k l e c e l l h a e m o g l o b i n , a r e t h e products of al ternate globin chain genes ...

An international consensus statement recommends that dual reporting of haemoglobin A (HbA(1c)) levels--in the current units (percentage) and Système International (SI) units (mmol/mol)--be used as an interim measure for a 2-year transition period before progressing towards the use of SI units only. This recommendation is supported by the Australasian Association of Clinical Biochemists, the Aus...

background: reports on the determinants of morbidity in coronary artery bypass graft surgery (cabg) have focused on outcome measures such as length of postoperative stay in the intensive care unit (icu). we proposed that major comorbidities in the icu hampered the prognostic effect of other weaker but important preventable risk factors with effect on patients’ length of hospitalization. so we a...

General practice characteristics are important for healthcare providers to maximise outcomes. Although different aspects of general practice characteristics have been studied previously, the impact of practice size on the delivery of care has been sparsely studied, particularly in relation to diabetes care. This brief report presents a longitudinal study in Shropshire (66 practices, 16,858 pati...

OBJECTIVE Haemoglobin A1c (Hb A1c) is routinely used for monitoring glycemic control in patients with diabetes. Hb A1c seasonal fluctuations can be directly related to different biological, geographical and cultural influences. Our purpose was to evaluate seasonal variation of Hb A1c in a hospital-based adult population over a period of 5 years. MATERIALS AND METHODS We analyzed retrospective...

Concentrations of total glycosylated haemoglobins (Hb A1) were measured in 40 diabetics at diagnosis and at monthly intervals after treatment with chlorpropamide, insulin, or diet alone was begun. The mean Hb A1 concentration at presentation in 16 patients treated with chlorpropamide was significantly higher than that in 12 patients treated with insulin, and the duration of glycaemic symptoms w...

OBJECTIVE Examine clinical indicators to evaluate diabetes care in Mexico. MATERIAL AND METHODS Diabetics (self reported, with therapy) were examined with standardized questionnaires, anthropometry, glucose, lipids and glycohemoglobin. Data were analyzed statistically. RESULTS There were 2 644 patients, 677 cases without access to medical care (73% women), most lived in rural communities an...

Mothers who have big babies may have had abnormal glucose tolerance during pregnancy. Glycosylated haemoglobin (HbA1) concentrations were measured on the first or second day after delivery in 50 women who had had babies weighing over the 95th centile for gestational age and in 50 women who had had normal-sized babies (controls). Nine of the mothers of big babies but only one of the controls had...

www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 1379 in developing humans: the embryonic, Gower-I, Gower-II, Portland, fetal hemoglobin (HbF) and normal adult hemoglobin (HbA and HbA2). HbF is the primary hemoglobin found in the fetus. It has a higher affinity for oxygen than adult hemoglobin, thus increasing the efficiency of oxygen transfer to the fetus. The relative quantities of HbF rapidly decr...

The importance of education in the management of diabetes is recognised but has rarely been assessed in children. In a longitudinal controlled study we have examined the effect of a programme of education on the knowledge, diet, and concentration of glycated haemoglobin A1c in a group of diabetics. The programme took the form of two packages of education each consisting of four weekly meetings,...