BACKGROUND It is thought that a good survival rate of patients with acute liver failure can be achieved by establishing an artificial liver support system that reliably compensates liver function until the liver regenerates or a patient undergoes transplantation. We introduced a new artificial liver support system, on-line hemodiafiltration, in patients with acute liver failure. METHODS This ...

Introduction: Extensive hemolysis resulting in anuric renal failure is the main clinical sign of acute arsine poisoning. Plasmapheresis and exchange transfusion are recommended for patients with massive hemolysis. We report four cases of arsine exposure which demonstrate the effectiveness of continuous vein-venous hemodiafiltration and on-line hemodiafiltration for arsenic removal. Method: Bloo...

Carbamazepine (CBZ) intoxication is an important issue in acute poisoning practice. Highly protein-bound, CBZ is not removed efficiently through conventional hemodialysis. We describe the use of continuous venovenous hemodiafiltration (CVVHDF) in a 2-year-old boy who developed general tonic clonic seizure and respiratory depression due to controlled-release formula of CBZ overdose (peak drug le...

Abstract Background Low-ionized magnesium and high-ionized calcium levels are associated with increased cardiovascular mortality in patients undergoing dialysis. We examined the effects of dilution method, substitution volume, dialysate on-line hemodiafiltration on total ionized levels. Methods Eighteen were randomly assigned to three groups: two acetic acid groups one citrate group. Five treat...

BACKGROUND AND OBJECTIVE Low molecular weight heparins (LMWHs) are small enough to pass large pore dialysis membranes. Removal of LMWH if injected before the start of the session is possible during high-flux dialysis and hemodiafiltration. The aim of this study was to determine the optimal mode (place and time) of tinzaparin administration during postdilution hemodiafiltration. STUDY DESIGN, ...

background: acute blood purification (abp) therapy is used regularly in the clinical setting and reportedly alleviates organ failure associated with severe systemic inflammatory responses, leading to reduced mortality. the present study aimed to determine whether there is a difference in efficacy between polysulfone (ps) membranes, which are currently used regularly in the clinical setting, and...

Tumor necrosis factor (TNF-alpha) and interleukin-1 (IL-1 beta) are cytokines primarily produced by monocytes/macrophages when stimulated by endotoxin, complement-derived anaphylatoxins and the specific antigen. In the present study, the plasma levels of TNF-alpha and IL-1 beta were evaluated before and after hemodialysis with cuprophane membrane (in 9 patients) and hemodiafiltration (in 9 pati...