conclusions in iran, hsct has been successfully adapted in routine clinical care. recently, new methods such as double cord blood and haploidentical transplantation have been used to treat many life-threatening diseases. results about 78.2% of the patients (2530 of 3237) remained alive between one to 211 months after stem cell transplantation. nearly, 21.8% (707) of our patients died after stem...

Hematopoietic stem cell transplantation (HSCT) has been practiced for more than 30 years. Hematological malignanciesare the main indications for this treatment. However, its indications in adults are different from children.Advances in chemotherapy and target therapy have improved treatment outcome of some of the very high riskcancers, and changed indications of HSCT in children. Multi-center c...

Unlike in adults, the number of pediatric autologous hematopoietic stem cell transplants (HSCT) has decreased last years. This is because changing indications for this type treatment and new therapies available recent Polish HSCT centers have followed published recommendations Pediatric Hematopoietic Stem Cell Transplantation Group, which are generally based on European Society Blood Marrow ind...

Thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. For β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. Stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...

introduction: despite achievement to complete remission (cr) with current treatments and new multiple chemotherapeutic agents in acute lymphoblastic leukemia (all) patients, the majority of them still relapse during long-term follow-up. the use of post- remission therapy will reduce early relapse in these cases, but the best option is still debatable. patients and methods: in this retrospective...

Background: Burkitt lymphoma is a common subtype of non-Hodgkin lymphoma in children. It has a rapid and aggressive clinical course with frequent involvement of bone marrow and central nervous system. Systemic chemotherapy is the mainstay of the treatment for this malignancy in children. In this systematic review, we discuss autologous and allogeneic hematopoietic stem cell transplantation (HSC...

the aim of this study was to determine the incidence and causes of fever as a major problem contributing to transplantation related mortality among patients undergoing hematopoietic stem cell transplantation (hsct) and evaluation of antibiotic use, according to reliable guidelines.we retrospectively reviewed hospital records of 195 adult patients who underwent hsct between 2009-2011 at hematolo...

Hematopoietic stem cell transplantation (HSCT) is widely used to treat hematological malignancies and nonmalignant disorders. Many advances have been made in improving the success of bone marrow transplantation. However, lack available matched related or sibling donors has posed a significant challenges availability proper utilization hematopoietic patients with malignancies. The rising alterna...

Hematopoietic stem cell transplantation (HSCT) offers patients with malignant and nonmalignant diseases the oportunity to pursue life-prolonging therapy. The number of survivors after successful HSCT is continually increasing. However, HSCT can induce tissue and organ damage that occurs not only “on treatment” , but long after completing therapy. Secondary malignancies belong to serious late co...