UNLABELLED Twenty-eight patients (12 men with prostate cancer, 16 women with breast cancer) were included in a phase II trial to evaluate the efficacy of 186Re-hydroxyethylidene diphosphonate (HEDP) on pain from bone metastasis and the toxicity of this agent. METHODS After intravenous administration of 1295 MBq 186Re-HEDP, the efficacy was evaluated by means of a daily log. RESULTS We obser...

In this work, a bio-based flame retardant (Cy-HEDP) was synthesized from cytosine and HEDP through facile salt-forming reaction embedded into epoxy matrix to improve the retardancy smoke suppression performance. The product Cy-HEDP well characterized by FTIR, 1 H 31P NMR SEM tests. On basis of results, adding 15 wt% Cy-HEDP, EP15 can pass UL-94 V-0 rating, total production (TSP) as heat release...

The determination of trace organophosphonates which are used in cooling towers as a scale inhibitor usually involves extraction and/or concentration of the target components prior to analysis. The extracts are analyzed using chromatographic or spectroscopic methods. This methodology is not only cumbersome but also results in poor data quality. This work presents a novel approach for the rapid a...

UNLABELLED The clinical picture of bone metastases is manifested by pain and loss of mechanical stability. Standard treatment options for bone metastases include external beam radiotherapy and the use of analgesics. Due to a large number of lesions in many patients, the use of radionuclide therapy with beta emitters may be preferable. Re-186 hydroxyethylidene diphosphonate (Re-186 HEDP) is one ...

UNLABELLED The aim of this study was to introduce a new quantification method for 153Sm-ethylenediaminetetramethylenephosphonate (EDTMP) and 186Re-(tin)1,1-hydroxyethylidene diphosphonate (HEDP) to separately measure bone uptake and soft-tissue retention of these radiopharmaceuticals. METHODS Studies were performed on 23 men and 6 women undergoing radionuclide therapy for palliation of bone p...

Introduction: Bone metastases are the most common cause of cancer-related pain in various primary malignant tumors, most often, breast and prostate. 188Re-hydroxyethylidene diphosphonate (188Re-HEDP) is a new and less expensive bone seeking radiopharmaceutical with favorable physical characteristics of the radionuclide such as short half life of 16.9h, maximal β energy of ...

Hybrid CMOS (hCMOS) x-ray framing cameras are a new and powerful detector option for experiments in the fields of Inertial Confinement Fusion (ICF) High Energy Density Physics (HEDP). These digital capture multiple images along single line-of-sight with time resolution as short 1.5 ns high quantum efficiency. To manage data rate, an image sequence is acquired burst subsequently read out on much...