wounds and wound healing have always been one of the most important subjects that experimental researches were dedicated to. simvastatin has been used for long as a common lipid lowering agent which was reported to have some pleiotropic effects such as antioxidation, anti-inflammation and immunomodulation. in this study we aimed to determine the effect of simvastatin on wound healing process in...

burns are a worldwide problem. the incidence of severe burns has been higher than the combined incidence of tuberculosis and hiv infections. throughout history there have been many different treatments prescribed for burns. the canon is the masterpiece of avicenna’s medical books. the canon includes a description of 785 simple drugs. avicenna believed in burn treatment, which follows two goals....

background: cutaneous leishmaniasis (cl) is a parasitic disease in most parts of iran, especially in the isfahan province. the most common form of cl is a self-healing lesion but in rare situations, infection might develop to non-healing forms. clinical symptoms and treatment process might be influenced by several agents such as host immune response and parasite strains. in this study, the isol...

gum tragacanth is a natural complex mixture of polysaccharides and alkaline minerals extracted from species of astragalus plant, which is found widely in arid regions of the middle east. in a pilot experimental study we examined the effects of its topical application on wound healing in ten albino adult male rats. two similar parasagittal elliptical full-thickness wounds (control vs. test sampl...

conclusions the results showed the effectiveness of bromelain on episiotomy pain and wound healing. therefore, it is suggested to use bromelain in postoperative stage to improve wound healing and reduce pain. background ananas comosus has long been used for medical purposes. currently, we are experiencing an unprecedented interest in the use of complementary medicine as well as a growing attent...

objective: to determine the effects of topical administration of 20% oltipraz solution on histomorphometrical and stereological aspects of skin tissue in full thickness skin wounds in laboratory rats. methods: thirty-six male wistar portion rats (220±20 g) were randomly divided into three groups (n=12). on the first day of experimentation, a 1-cm 2 circular wound was made on the posterior surfa...

conclusions stem cell therapies in wound care may lessen the morbidities associated with wound healing. an ideal method for the effective administration of stem cells for burn patients has not yet been elucidated. further comparison of the local and systemic effects in burn patients, associated with each route of stem cell delivery, needs to be performed. results application of cells to the bur...

abstract background: pressure ulcers’ treatment imposes a considerable cost on health system and patients. electrical stimulation has already been introduced as an effective method for promoting wound healing. this study was conducted to determine the impact of interferential current (if) on healing of pressure ulcers (grade1 and 2). materials and methods: in this clinical trial, 23 patients (1...

introduction: different modalities have been used to achieve better results in wound healing among which are laser and pharmacological agents. to our knowledge, there is no investigation to compare phenytoin and laser together. in this study, we aimed to evaluate laser and phenytoin efficacy and compare their effect on wound healing. methods: we used 60 rats. the animals were divided into 4 gro...