background and aims: the aim of this study was to determine the correlation between the hepatitis b virus surface ag (hbsag) genotypes and variations in the clinical/serological pictures among hbsag positive chronic patients from south khorasan province of iran. methods: twenty-five patients were enrolled in this study. the hbs ag gene was amplified and was directly sequenced. genotypes and nuc...

mutations in the human hepatitis b virus (hbv) genome contribute to its escape from host immune surveillance and result in persistent infections. the aim of this study was to characterize the molecular variations of the surface gene and protein in chronically-infected patients from the southern part of iran. the  surface  genes  from  12  hbv  chronic  carriers  were  amplified, sequenced  and ...

Background: The risk of infection by transfusion-transmitted viruses has been reduced remarkably. However, a zero-risk blood supply is still desirable. The screening for antibody to HBc (anti-HBc) has been shown as an alternative test for the detection of HBV infection. Objective: The main aim of this study was to evaluate HBV infection markers and the potential value of anti-HBc testing of blo...

 ABSTRACT One of the best reliable markers of hepatitis B virus infection is antibodies to the core antigen (Anti-HBc). A first-time blood donor with HBsAg positivity was identified as an HBV carrier that was anti-HBc negative. The patient was followed for 24 months in order to investigate the evolution of his HBV serological profiles and HBVDNA (PCR). In the follow-up for 24 months, HBsAg, HBe...

Advanced studies have shown a biological correlation between hepatitis B virus (HBV) and B-cell lymphoma, especially diffuse large lymphoma (DLBCL). Patients with DLBCL infected HBV (HBV-associated DLBCL) are clinically characterized by an advanced clinical stage, poor response to front-line immunochemotherapy regimens, worse prognosis. HBV-associated often exhibits abnormal activation of the n...

Abstract. Information about the spatiotemporal variability of soil moisture is critical for many purposes, including monitoring hydrologic extremes, irrigation scheduling, and prediction agricultural yields. We evaluated temporal dynamics 18 state-of-the-art (quasi-)global near-surface products, six based on satellite retrievals, models without data assimilation (referred to hereafter as “open-...

Abstract Hepatitis B virus (HBV) increases morbidity and mortality among people living with HIV (PLWH). We retrospectively analyzed HBV incidence 5,785 PLWH. Fourteen had newly positive HBsAg (mean 5.2 person-years of follow-up, 46.4/100,000 infections/year). These data show gaps in vaccination the preventative efficacy HBV-specific ART.

Abstract An estimated 296 million people worldwide suffer from chronic hepatitis B virus (HBV) infection, with 1.5 new infections occurring each year despite the availability of an effective vaccine. Chronic HBV infection persists in a dysfunctional immune environment, manifested by ineffective T cell response to virus. Patient HBV-specific CD8 +T cells have diminished proliferative capacity an...