BACKGROUND Oral challenges are the gold standard in food allergy diagnostic, but time-consuming. Aim of the study was to investigate the role of peanut- and hazelnut-component-specific IgE in the diagnostics of peanut and hazelnut allergy and to identify cutoff levels to make some challenges superfluous. METHODS In a prospective and multicenter study, children with suspected peanut or hazelnu...

hazelnut (corylus avellna l.) is one of the important nut crops in world. the harvesting ofhazelnuts is done either by hand or by manual or mechanical raking of fallen nuts in iran.common hazel is widely cultivated for its nuts, including in commercial orchards in europe,turkey, and iran. there are some genotypes of hazelnut in iran that their growing areas arelimited to gillan, aredbil, mazand...

BACKGROUND Sensitization to hazelnut allergens vary depending on the geographic origin and age of the patients. The objective of this study was to further investigate the allergenic activity of hazelnut allergens using sera from patients recruited in various European regions and presenting different sensitization patterns to hazelnut proteins. METHODS Natural Cor a 11 and Cor a 9 were purifie...

BACKGROUND Hazelnut (Corylus avellana) allergy exhibits age and geographically distinct sensitization patterns that have not yet been fully resolved. OBJECTIVE To study sensitization to Cor a 11 in different age groups of hazelnut-allergic patients and infants with atopic dermatitis (AD) sensitized to hazelnut in a birch-endemic region. METHODS Sera from 80 hazelnut-allergic patients, 33 in...

BACKGROUND Oil body-associated allergens such as oleosins have been reported for important allergenic foods such as peanut, sesame and hazelnut. Here we investigate whether oil body associated proteins (OAPs) are linked with specific clinical phenotypes and whether they are represented in skin prick test (SPT) reagents. METHODS A hazelnut OAP fraction was characterized by mass-spectrometry (M...

The present work concerns the experimental evaluation of hazelnut shells as a low cost natural biosorbent. Adsorption of the direct azo dye Congo Red was performed within a concentrations range of 50-5000 mg/L. Hazelnut shells were employed as organic support for Phanerochaete chrysosporium cultures to study the best cultural medium composition for the MnP production. The capability of Phaneroc...

The fraudulent addition of hazelnut oil to more expensive olive oil not only causes economical loss but may also result in problems for allergic individuals as they may inadvertently be exposed to potentially allergenic hazelnut proteins. To improve consumer safety, a rapid and sensitive direct biosensor immunoassay, based on a highly specific monoclonal antibody, was developed to detect the pr...

Food allergies to hazelnut represent an important health problem in industrialized countries because of their high prevalence and severity. Food allergenicity can be changed by several processing procedures since food proteins may undergo modifications which could alter immunoreactivity. High-hydrostatic pressure (HHP) is an emerging processing technology used to develop novel and high-quality ...

BACKGROUND Clinically it is recognized that tree nut allergies such as hazelnut allergy are not usually outgrown. Specific mechanisms underlying the persistence of such food allergies are incompletely understood. Here we studied the natural history and the long-term immune and clinical characteristics of hazelnut allergy in an adjuvant-free mouse model. METHODS BALB/c mice were sensitized to ...

Pseudomonas avellanae (Pav) has been reported as the causal agent of bacterial decline and bacterial canker of hazelnut in Italy and Greece, respectively. Both hazelnut diseases were reported to be similar in terms of symptoms, severity and persistence. In this study, we found that both symptomatic and asymptomatic trees in the field were colonized by Pav. Multilocus Sequence Typing (MLST) anal...