a 3.5 month-old girl was admitted with silvery gray hair, light  colored skin, recurrent diarrhea, chest infections, hepatosplenomegaly, episodes of pancytopenia, and hemophagocytosis in the bone marrow. light microscopy of hair showed characteristic large and irregular clumps of melanin in the middle of hair shaft. peripheral blood smear examination did not show giant granules in granulocytes....

Background: Pilomatricoma, the most common hair follicle tumor, has a wide variety of clinicopathological characteristics and is often misdiagnosed. Objective: The aim of this study was to explain the clinical and histological spectrum of tumor in order to help for its better diagnosis. Patients and Methods: In a retrospective descriptive study, the clinical and histological features of pilomat...

A 28 year old albino man presented with a cicatricial alopecic plaque on the vertex. The patient had multiple hairs emerging from a single dilated follicular opening. Following inflammatory changes, new tufted hair appeared in spite of several periods of antibiotic treatment, and the disorder followed a relapsing and destructive course. Tufted hair folliculitis (THF) is a relapsing localiz...

Background: Worldwide, coronary heart disease is the most important cause of mortality and morbidity. Although numerous studies have documented the relationship between male pattern baldness and cardiovascular disease (CVD), few studies focused on this association in women. This study intended to evaluate the relationship between coronary artery disease and androgenetic alopecia (AGA) in ...

Cartilage hair hypoplasia (CHH), is a rare cause of metaphyseal chondrodysplasia and short stature. Other featuresincluded hair abnormality, immunodeficiency, anemia, gastrointestinal disorders (Hirschsprung disease,celiac, …) and increased risk of cancer. The disease is an autosomal recessive disorder and previously has notbeen reported in Iran. We report a 9-year-old boy diagnosed as cartilag...

Objective(s): Chronic liver disease has become a major health problem that causes serious damage to human health. Since the existing treatment effect was not ideal, we need to seek new treatment methods. Materials and Methods: We utilized the gene recombination technology to obtain the human hair mesenchymal stem cells which overexpression of human hepatocyte growth factor (hHGF). Furthermore, ...

J Balaji and P Amutha Rajeshwari, Institute of Child Health and Research Centre, Government Rajaji Hospital and Madurai Medical College, Madurai. Tamil Nadu, India. [email protected] FIG.1 A child with Hypomelanosis of Ito showing multiple whorled like hypopigmented lesions present over abdomen, chest and back. FIG.2 Fundus showing pale disc, tortous vessels around the disc, radial patchy ...