guillain barre syndrome (gbs) is an inflammatory, usually demyelinating, polyneuropathy; clinically characterized by acute onset of symmetric progressive muscle weakness with loss of myotatic reflexes. thirty five patients with gbs, defined clinically according to the criteria of asbury and cornblath, were recruited from three hospital affiliated to tehran university of medical sciences.as a co...

conclusions we found ccd and rsm very effective in optimizing hib culture conditions, and hib biomass production was greatly influenced by ph and incubation temperature. therefore, optimization of the growth factors to maximize hib production can lead to 1) an increase in bacterial biomass and prp productions, 2) lower vaccine prices, 3) vaccination of more susceptible populations, and 4) lower...

in the present study, seven isolates of haemophilus influenzae type b were cultured in four different media to compare growth rate and capsule production. four liquid media namely brain heart infusion broth (bhi), trypticase soy broth (tsb), mueller hinton broth (mhb) and gonococci broth (gc) with added supplements (1% hemoglobin, 1% isovitalex) were used. the growth was measured by colony coun...

haemophilus influenzae, a major cause of meningitis in young children leading to death and other neurological sequelae. the disease leaves 15 to 35% of the survivors with permanent disabilities, such as, mental retardation or deafness. despite the availability of new and more powerful antibiotics children with hib meningitis still suffer from high mortality or morbidity. the emergence of multir...