Haemophilia patients experience acute pain during joint bleeds and chronic pain from haemophilic arthropathy. More than 50% of haemophilia patients have painful joints that cause disability and impair quality of life. Unfortunately, only a few clinical studies have investigated the non-pharmacological or pharmacological treatments for pain or the adverse effects of pain on the health and qualit...

Introduction Detection of early arthropathy is crucial for the management haemophilia, but data on moderate haemophilia are limited. Therefore, we evaluated joint health and treatment modalities in Nordic patients with A (MHA) B (MHB). Aim To explore compare Haemophilia Early Arthropathy Ultrasound (HEAD-US) Joint Health Score (HJHS) to detect haemophilia. Methods cross-sectional, multicentre s...

Advances in therapy have improved life expectancy and quality of life of patients with haemophilia A. Due to the chronic and complex management of this disease, particularly, the development of inhibitors, little is known about their health resource utilization in the real-life setting over time. The aim was to assess the distribution and trend of healthcare resource utilization among US haemop...

Quality of life (QoL) is a multidimensional construct pertaining to an individual's physical, emotional, mental, social and behavioural components of well-being and functioning. QoL can be assessed using both generic and disease-specific instruments. QoL assessment in haemophilia is a relatively new area of study; the first data were published in 1990 using generic QoL questionnaires. Only rece...

Owing to the improvements in the management of haemophilia, children with severe haemophilia in the United Kingdom have very different experiences of their condition compared with many adults' early experiences of haemophilia. However, haemophilia can still have physical and social effects which can impact on the quality of life, not only for a child who has the condition, but also for their pa...

BACKGROUND Haemophilia is a rare hereditary haemorrhagic disease that requires regular intravenous injections of clotting factor (CF) concentrates. This study sought to estimate the health and economic burden of haemophilia in Belgium. This is the first study of its type to be conducted, and reflects the Belgian authorities' growing interest for haemophilia as part of their priority planning fo...

Introduction One of the most often stated tenets haemophilia care is that prophylaxis converts a person from severe to moderate phenotype. In this review, we argue not an accurate assumption and people on predominantly have factor VIII/IX levels in mild range. Moderate People with haemophilia, who are treating on-demand regimens, experience joint bleeds develop significant arthropathy. This esp...

conclusions although differences between the two products were very close to each other, they reported similar effects on joint bleeds. further clinical studies should be performed by incorporating a standardized measurement in comparative efficacy of apcc and rfviia. results the mean of bleeding reduction in apcc and rfviia were 71.2% with ci 95% (lower limit 86.8% and upper limit 82%) and 72....

The problems caused by haemophilia lead to impairments of the quality of life in patients with haemophilia. This study aimed to investigate the effects of yoga on quality of life in the children and adolescents with haemophilia in Shiraz, Iran. This semi-experimental study with pre- and post-test design was performed on 27 boys between 8 and 16 years old who suffered from haemophilia. The patie...

Current treatments in the field of haemophilia are changing phenotype many patients with severe to that mild haemophilia. Despite this improvement, those mild-to-moderate A and B continue experience unmet needs. Whereas some similar complications haemophilia, they possess several unique attributes. These include a challenging diagnosis variability bleeding symptoms treatment In addition, is an ...