<!-- .article-title, .h1-h2-after, .h1, .h1-references, .bib-doi { color:#2d7db5; } white-space:nowrap; .h1-references font-size:1.6rem; line-height:1.5em; font-weight:700; margin:0 0 0.5em 0; .h1-h2-after margin-bottom:0; .h2, .

this study considers scheduling in hybrid flow shop environment with unrelated parallel machines for minimizing mean of job&apos;s tardiness and mean of job&apos;s completion times. this problem does not study in the literature, so far. flexible flow shop environment is applicable in various industries such as wire and spring manufacturing, electronic industries and production lines. after mode...

Two cDNA clones isolated from a HepG2 lambda gt11 library encode the classical asialoglycoprotein receptor, H1, as well as a homologous membrane glycoprotein, H2 (Spiess, M., and Lodish, H.F. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 6465-6469). To study the relationship of H2 to H1 and its possible role in receptor-mediated endocytosis of desialyated glycoproteins, we generated anti-peptide ant...

Antibody-induced degradation and chemical cross-linking experiments have been carried out to assess the nature of the interaction between the two asialoglycoprotein-receptor polypeptides, H1 and H2, synthesized in HepG2 cells. Incubation of HepG2 cell monolayers with anti-H1 antibody caused a specific and equal loss of both H1 and H2 polypeptides. The same result was obtained with anti-H2 antib...

The human asialoglycoprotein receptor, an endocytic transport receptor of the basolateral surface of hepatocytes, is a hetero-oligomer of two homologous subunits H1 and H2. The cytoplasmic domain of H1 has been shown previously to contain a tyrosine-based signal for endocytosis and basolateral sorting. Here, we have investigated sorting determinants within subunit H2 and their contribution to t...

Given two graphs H1 and H2, a graph G is (H1,H2)-free if it contains no subgraph isomorphic to H1 or H2. We continue a recent study into the clique-width of (H1,H2)-free graphs and present three new classes of (H1, H2)-free graphs that have bounded clique-width. We also show the implications of our results for the computational complexity of the Colouring problem restricted to (H1,H2)-free grap...

In barley (Hordeum vulgare), PHOTOPERIOD1 (Ppd-H1) acts as a major positive regulator of flowering under long-day conditions, while VERNALIZATION2 (VRN-H2) is a strong repressor of flowering under long days before vernalization. By contrast, CONSTANS (CO) plays a key role in the photoperiodic regulation of flowering in Arabidopsis (Arabidopsis thaliana). Here, we study the role of the closest b...

Biomolecular recognition entails attractive forces for the functional native states and discrimination against potential nonnative interactions that favor alternate stable configurations. The challenge posed by the competition of nonnative stabilization against native-centric forces is conceptualized as frustration. Experiment indicates that frustration is often minimal in evolved biological sy...

Neurofibrillary tangles composed of exon 10+ microtubule associated protein tau (MAPT) deposits are the characteristic feature of the neurodegenerative diseases progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). PSP, CBD and more recently Alzheimer's disease and Parkinson's disease, are associated with the MAPT H1 haplotype, but the relationship between genotype and disea...

The relative magnitude of the first two harmonics of the voice source (H1*-H2*) is an important measure and is assumed to be one exponent of changes in vocal quality along a breathyto-pressed continuum. H1*-H2* is often associated with glottal open quotient (OQ) and glottal pulse skewness (as quantified by speed quotient, SQ), but may also covary with fundamental frequency (F0) and vocal intens...