Colorectal cancer is one of the most common types of cancer in the world and its morbidity and mortality rates are increasing due to alterations to human lifestyle and dietary habits. The relationship between human gut flora and colorectal cancer has attracted increasing attention. In the present study, a metabolic fingerprinting technique that combined pyrosequencing with gas chromatography-ma...

In a recent publication, we reported the identification and characterization of two distinct phenotypes in SpragueDawley rats obtained from the Charles River Raleigh facility (Robosky et al., 2005). The phenotypes were designated as HIP (high hippuric acid level in urine) and CA (high chlorogenic acid metabolites level in urine). The endogenous urinary metabolic profile of each phenotype was di...

In this review, the factors thought to be important in deter mining the composition of the gut bacterial flora are discussed. In the light ofthese, the effects of various dietary manipulations on the composition and metabolic activity of the gut flora are described. In general, the main effects of diet would be ex pected to be manifested in the right colon, whereas the material available for in...

The human gastrointestinal tract harbors a diverse, highly mutualistic microbial flora which could produce a myriad of specialized metabolites. These specialized metabolites are the chemical cellphones that gut microflora use to communicate with their human host and could potentially be used to cure diseases. Chemical compounds in diet also shape the gut flora. In order to understand which and ...

Objective(s): Recent evidence has shown underlying roles of gut dysbiosis and metabolic endotoxemia in obesity and its complications. Despite the large number of experimental and clinical researches performed on gut microbiota and obesity, no bibliometrics’ study has been conducted so far. We aimed to assess the trend of global scientific publications in the field of gut microbiota and obesity....

Our intestines are habitat for trillions of microorganisms such as bacteria, viruses and eukaryotes, known as microbiota. They are indispensable for our well-being due to their metabolic activities. Microbiota digests complex plant polysaccharides, which are normally unprocessed by humans; as well it retrieves other essential nutrients. It is well established that microbiota is crucial for prop...

BACKGROUND The purpose of this review was to identify the relationship between the gut microbiome and the development of postoperative complications like anastomotic leakage or a wound infection. Recent reviews focusing on underlying molecular biology suggested that postoperative complications might be influenced by the patients' gut flora. Therefore, a review focusing on the available clinical...