نتایج جستجو برای: guanidines

تعداد نتایج: 348  

2017
Vjekoslav Štrukil

In this review, the recent progress in the synthesis of ureas, thioureas and guanidines by solid-state mechanochemical ball milling is highlighted. While the literature is abundant on their preparation in conventional solution environment, it was not until the advent of solvent-free manual grinding using a mortar and pestle and automated ball milling that new synthetic opportunities have opened...

Journal: :Canadian Journal of Chemistry 1960

Journal: :Agricultural and Biological Chemistry 1970

Journal: :Canadian Journal of Chemistry 1958

Journal: :The Journal of organic chemistry 1999
Alison S. Franklin Sylvie K. Ly Gilbert H. Mackin Larry E. Overman A. J. Shaka

Tethered Biginelli condensation of enantioenriched hexahydropyrrolopyrimidines 8 with beta-ketoesters provides efficient asymmetric access to tricyclic guanidines 9 having a syn relationship of the angular C2a and C8a hydrogens. This reaction was employed to realize the first practical enantioselective access to this fragment of batzelladine alkaloids B (2) and E (5). The efficiency of this str...

Journal: :Archiv der Pharmazie 2007
Sheng-Xue Xie Fabian Schalkhausser Qi-Zhuang Ye Roland Seifert Armin Buschauer

Imidazolylpropylguanidines derived from impromidine and arpromidine are more potent and efficacious agonists at the guinea pig histamine H2 receptor (gpH2R) than at the human H2R (hH2R) in the GTPase assay. Additionally, such guanidines are histamine H1 receptor (H1R) antagonists with preference for the human relative to the guinea pig receptor. The purpose of this study was to examine structur...

Journal: :Canadian Journal of Chemistry 1967

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